Evidence map›Paper›PMID 33809893›Full record

ArticleCells2021

Direct Stimulatory Effects of the CB

Inmaculada Ruz-Maldonado, Patricio Atanes, Guo Cai Huang, Bo Liu, Shanta J Persaud

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Inmaculada Ruz-MaldonadoDepartment of Diabetes, School of Life Course Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.ORCID 0000-0002-2858-8446
Patricio AtanesDepartment of Diabetes, School of Life Course Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Guo Cai HuangDepartment of Diabetes, School of Life Course Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Bo LiuDepartment of Diabetes, School of Life Course Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Shanta J PersaudDepartment of Diabetes, School of Life Course Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
King's College London · GB

Funding

Diabetes UK 11/0004307Wellcome Trust
6 · The paper itself

Abstract

aimsThe endocannabinoid system is a complex cell-signaling network through which endogenous cannabinoid ligands regulate cell function by interaction with CB MATERIALS AND

methodsWe used islets isolated from human donors and from

resultsJTE 907 significantly stimulated insulin secretion from islets isolated from human donors and islets from

conclusionOur observations show for the first time that JTE 907 acts as a G

Indexed as

AdultAnimalsApoptosisCalcium SignalingCannabinoid Receptor AgonistsCell ProliferationDioxolesFemaleHumansInositol PhosphatesInsulinIslets of LangerhansLigandsMaleMiceMice, Inbred C57BLCannabinoid Receptor AgonistsDioxolesGPR55 protein, humanGPR55 protein, mouseinositol 1-phosphateInositol PhosphatesInsulinJTE 907LigandsQuinolonesReceptors, Cannabinoidapoptosiscannabinoid G protein-coupled receptorshuman isletsinsulin secretionproliferation

Identifiers

PMID33809893
PMCPMC8004177
OpenAlexW3136413621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.