Evidence map›Paper›PMID 33809852›Full record

ArticleCancers2021

Prediction of Unplanned Hospitalizations in Older Patients Treated with Chemotherapy.

Jaime Feliu, Enrique Espinosa, Laura Basterretxea, Irene Paredero, Elisenda Llabrés, Beatriz Jiménez-Munárriz, Beatriz Losada, Alvaro Pinto, Ana Belén Custodio, María Del Mar Muñoz and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Jaime FeliuOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.ORCID 0000-0003-4867-1420
Enrique EspinosaOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.
Laura BasterretxeaOncology Department, Hospital Universitario de Donostia, 20014 Donostia, Spain.
Irene ParederoOncology Department, Hospital Universitario Dr. Peset, 46017 Valencia, Spain.ORCID 0000-0003-3618-8685
Elisenda LlabrésOncology Department, Hospital Universitario Insular de Gran Canarias, 35016 Las Palmas, Spain.
Beatriz Jiménez-MunárrizOncology Department, Centro Integral Oncológico Clara Campal, 28050 Madrid, Spain.
Beatriz LosadaOncology Department, Hospital Universitario de Fuenlabrada, 28942 Fuenlabrada, Spain.ORCID 0000-0001-9283-4333
Alvaro PintoOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.
Ana Belén CustodioOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.
María Del Mar MuñozOncology Department, Hospital Virgen de la Luz, 16002 Cuenca, Spain.
Jeniffer Gómez-MediavillaOncology Department, Hospital Universitario de Donostia, 20014 Donostia, Spain.
María Dolores TorregrosaOncology Department, Hospital Universitario Dr. Peset, 46017 Valencia, Spain.
Patricia CruzOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.
Oliver HigueraOncology Department, Hospital Universitario La Paz. IDIPAZ, Cátedra UAM-AMGEN, Centro de Investigación Biomédica en Red de Cáncer, 28046 Madrid, Spain.
María José Molina-GarridoOncology Department, Hospital Virgen de la Luz, 16002 Cuenca, Spain.
Hospital Universitario La Paz · ESDonostiako Unibertsitate Ospitalea · ESHospital Universitario Doctor Peset · ESHospital Virgen de la Luz · ESCentro Oncológico de Galicia · ESHospital Universitario de Fuenlabrada · ESHospital Universitario Insular de Gran Canaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the incidence of unplanned hospitalization (UH) and to identify risk factors for UH in elderly patients with cancer who start chemotherapy.

methodsIn all, 493 patients over 70 years starting new chemotherapy regimens were prospectively included. A pre-chemotherapy geriatric assessment was performed, and tumor and treatment variables were collected. The association between these factors and UH was examined by using multivariable logistic regression. Score points were assigned to each risk factor.

resultsDuring the first 6 months of treatment, 37% of patients had at least one episode of UH. Risk factors were the use of combination chemotherapy at standard doses, a MAX2 index ≥1, a Charlson comorbidity score ≥2, albumin level <3.5 g/dL, falls in the past 6 months ≥1, and weight loss >5%. Three risk groups for UH were established according to the score in all patients: 0-1: 17.5%; 2: 34%; and 3-7: 57% (

conclusionThis simple tool can help to reduce the incidence of UH in elderly patients with cancer who are scheduled to initiate chemotherapy treatment.

Indexed as

chemotherapygeriatric assessmentolder patientrisk scoreunplanned hospitalizations

Identifiers

PMID33809852
PMCPMC8004134
OpenAlexW3136000239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.