Evidence map›Paper›PMID 33809822›Full record

ArticleVeterinary sciences2021

A Retrospective Multicentric Study of Electrochemotherapy in the Treatment of Feline Nasal Planum Squamous Cell Carcinoma.

Petra Simčič, Alessio Pierini, George Lubas, Ron Lowe, Valentina Granziera, Raimondo Tornago, Fabio Valentini, Giulia Alterio, Matteo Cochi, Marcelo Monte Mor Rangel and 7 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Petra SimčičDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, San Piero a Grado, 56122 Pisa, Italy.ORCID 0000-0002-6592-8219
Alessio PieriniDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, San Piero a Grado, 56122 Pisa, Italy.ORCID 0000-0002-9336-5150
George LubasDepartment of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, San Piero a Grado, 56122 Pisa, Italy.ORCID 0000-0002-9430-1060
Ron LowePetCancerVet, 61 Wetherby Road, Knaresborough, North Yorkshire HG5 8LH, UK.
Valentina GranzieraPetCancerVet, 61 Wetherby Road, Knaresborough, North Yorkshire HG5 8LH, UK.
Raimondo TornagoMeranese Veterinary Centre, Via J. Speckbacher, 15/B, 39012 Merano, Italy.
Fabio ValentiniVia Marco Cornelio Cetego 20, 00177 Rome, Italy.
Giulia AlterioVia Marco Cornelio Cetego 20, 00177 Rome, Italy.
Matteo CochiVia Marco Cornelio Cetego 20, 00177 Rome, Italy.
Marcelo Monte Mor RangelVet Câncer-Animal Oncology and Pathology, AL Jauaperi, 732 Moema, São Paulo, SP 04523-013, Brazil.ORCID 0000-0003-3714-9215
Krishna Duro de OliveiraVet Câncer-Animal Oncology and Pathology, AL Jauaperi, 732 Moema, São Paulo, SP 04523-013, Brazil.
Jennifer Ostrand FreytagVet Câncer-Animal Oncology and Pathology, AL Jauaperi, 732 Moema, São Paulo, SP 04523-013, Brazil.
Priscila Gil QuadrosVet Câncer-Animal Oncology and Pathology, AL Jauaperi, 732 Moema, São Paulo, SP 04523-013, Brazil.
Enrico SponzaVeterinary Facility Dr. Enrico Sponza, Via Pra' 39/r, 16157 Genova, Italy.
Francesca GattinoVeterinary Facility Dr. Enrico Sponza, Via Pra' 39/r, 16157 Genova, Italy.
Joseph A ImpellizeriVeterinary Oncology Services, PLLC at Guardian Veterinary Specialists, Brewster, NY 10509, USA.
Filippo TorrigianiDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-2601-684X
University of Pisa · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline squamous cell carcinoma (SCC) is currently treated with surgery, radiation therapy and electrochemotherapy (ECT). Both the efficacy and/or safety of ECT were evaluated as a sole therapy with bleomycin to treat feline nasal planum SCC (npSCC). Sixty-one cats were enrolled. Local treatment response was evaluated as complete remission (CR), partial remission (PR) or stable disease (SD). Recurrence rate (RR), disease-free interval (DFI) and progression free survival (PFS) were calculated. A six-point scale was used for ECT toxicity. The median tumor size was 1.5 cm. CR was achieved in 65.6% of cases, PR in 31.1% and SD in 3.3%. The overall response rate was 96.7%, RR was 22.5%, median DFI was 136 days, and median PFS was 65.5 days. ECT toxicity was ≤2 in 51% of cats. Tumor recurrence/progression (

Indexed as

bleomycinelectrochemotherapyfelinemulticentricnasal planumretrospectivesquamous cell carcinomatoxicity

Identifiers

PMID33809822
PMCPMC8004260
OpenAlexW3136852421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.