Evidence map›Paper›PMID 33809750›Full record

ArticleCancers2021

Functional Genetic Variants in

Isabel Castro, Belém Sampaio-Marques, Anabela C Areias, Hugo Sousa, Ângela Fernandes, José Manuel Sanchez-Maldonado, Cristina Cunha, Agostinho Carvalho, Juan Sainz, Paula Ludovico

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. The dual role of autophagy in acute myeloid leukemia.Journal of hematology & oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Isabel CastroLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Belém Sampaio-MarquesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-6580-0971
Anabela C AreiasLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-1807-7386
Hugo SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-5795-2131
Ângela FernandesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-8255-5602
José Manuel Sanchez-MaldonadoGenomic Oncology Area, GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS, Avda. de la Ilustración, 114, 18016 Granada, Spain.
Cristina CunhaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Agostinho CarvalhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-8935-8030
Juan SainzGenomic Oncology Area, GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS, Avda. de la Ilustración, 114, 18016 Granada, Spain.ORCID 0000-0002-9355-2423
Paula LudovicoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0003-4130-7167
University of Minho · PTi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTInstituto de Investigación Biosanitaria de Granada · ESInstituto Português de Oncologia Francisco Gentil · PTUniversidad de Granada · ES

Funding

Fondo de Investigaciones Sanitarias (Madrid, Spain) ISCIII-FEDER PI12/02688Fondo de Investigaciones Sanitarias (Madrid, Spain) ISCIII-FEDER PI17/02276Fondo de Investigaciones Sanitarias (Madrid, Spain) ISCIII-FEDER PI20/01845Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-028159Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-030782
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is the most common acute leukemia, characterized by a heterogeneous genetic landscape contributing, among others, to the occurrence of metabolic reprogramming. Autophagy, a key player on metabolism, plays an essential role in AML. Here, we examined the association of three potentially functional genetic polymorphisms in the

Indexed as

acute myeloid leukemiaATG10autophagysingle nucleotide polymorphism

Identifiers

PMID33809750
PMCPMC8002222
OpenAlexW3139101533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.