Evidence map›Paper›PMID 33809710›Full record

ArticleSensors (Basel, Switzerland)2021

Deep Learning Automated Segmentation for Muscle and Adipose Tissue from Abdominal Computed Tomography in Polytrauma Patients.

Leanne L G C Ackermans, Leroy Volmer, Leonard Wee, Ralph Brecheisen, Patricia Sánchez-González, Alexander P Seiffert, Enrique J Gómez, Andre Dekker, Jan A Ten Bosch, Steven M W Olde Damink and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05496777 (Feasibility of Supervised Home-based Exercise Prehabilitation in Patients Scheduled for Pancreatic Resection), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05496777 nacompletednot on this mapstarted 2022, after this paper: background citation

Feasibility of Supervised Home-based Exercise Prehabilitation in Patients Scheduled for Pancreatic Resection

TypeinterventionalSponsorNicole HildebrandRan2022 to 2023Enrolled45ConditionsPreoperative Physical Exercise Training, Aerobic Capacity, Aerobic Fitness, Functional MobilityArmsHome-based prehabilitation program
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leanne L G C AckermansDepartment of Traumatology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.
Leroy VolmerDepartment of Radiation Oncology (MAASTRO), GROW School for Oncology and Development Biology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.
Leonard WeeDepartment of Radiation Oncology (MAASTRO), GROW School for Oncology and Development Biology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0003-1612-9055
Ralph BrecheisenDepartment of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0001-9937-2602
Patricia Sánchez-GonzálezBiomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-9871-0884
Alexander P SeiffertBiomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-7274-244X
Enrique J GómezBiomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
Andre DekkerDepartment of Radiation Oncology (MAASTRO), GROW School for Oncology and Development Biology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-0422-7996
Jan A Ten BoschDepartment of Traumatology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-6195-9704
Steven M W Olde DaminkDepartment of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-5202-9345
Taco J BlokhuisDepartment of Traumatology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-3601-3458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manual segmentation of muscle and adipose compartments from computed tomography (CT) axial images is a potential bottleneck in early rapid detection and quantification of sarcopenia. A prototype deep learning neural network was trained on a multi-center collection of 3413 abdominal cancer surgery subjects to automatically segment truncal muscle, subcutaneous adipose tissue and visceral adipose tissue at the L3 lumbar vertebral level. Segmentations were externally tested on 233 polytrauma subjects. Although after severe trauma abdominal CT scans are quickly and robustly delivered, with often motion or scatter artefacts, incomplete vertebral bodies or arms that influence image quality, the concordance was generally very good for the body composition indices of Skeletal Muscle Radiation Attenuation (SMRA) (Concordance Correlation Coefficient (CCC) = 0.92), Visceral Adipose Tissue index (VATI) (CCC = 0.99) and Subcutaneous Adipose Tissue Index (SATI) (CCC = 0.99). In conclusion, this article showed an automated and accurate segmentation system to segment the cross-sectional muscle and adipose area L3 lumbar spine level on abdominal CT. Future perspectives will include fine-tuning the algorithm and minimizing the outliers.

Indexed as

Deep LearningMultiple TraumaAdipose TissueCross-Sectional StudiesHumansMuscle, SkeletalTomography, X-Ray Computedautomated segmentationcomputed tomographydeep learning neural networksarcopenia

Identifiers

PMID33809710
PMCPMC8002279

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.