Evidence map›Paper›PMID 33809698›Full record

ArticleJournal of clinical medicine2021

Physical Exercise Moderates the Effects of Disability on Depression in People with Multiple Sclerosis during the COVID-19 Outbreak.

Antonio Carotenuto, Cristiano Scandurra, Teresa Costabile, Luigi Lavorgna, Giovanna Borriello, Lucia Moiola, Matilde Inglese, Francesca Trojsi, Martina Petruzzo, Antonio Ianniello and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
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  7. Exploring COVID-19 experiences for persons with multiple sclerosis and carers: An Australian qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 1 country.

Antonio CarotenutoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-1574-9693
Cristiano ScandurraDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-1790-3997
Teresa CostabileMultiple Sclerosis Centre, II Division of Neurology, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Luigi LavorgnaDepartment of Advanced Medical and Surgical Sciences, II Clinic of Neurology, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0003-4625-4236
Giovanna BorrielloMS Center, S. Andrea Hospital, Sapienza University, 00189 Rome, Italy.
Lucia MoiolaNeurology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Matilde IngleseDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DNOGMI), University of Genoa, 16132 Genoa, Italy.
Francesca TrojsiDepartment of Advanced Medical and Surgical Sciences, II Clinic of Neurology, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-3790-8018
Martina PetruzzoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
Antonio IannielloMS Center, S. Andrea Hospital, Sapienza University, 00189 Rome, Italy.ORCID 0000-0001-8433-0944
Agostino NozzolilloNeurology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Maria CellerinoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DNOGMI), University of Genoa, 16132 Genoa, Italy.
Giacomo BoffaDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DNOGMI), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-2220-9422
Laura RosaInterUniversity Center for Research in Neurosciences (CIRN), University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Alessandro ChiodiIntradepartmental Program of Clinical Psychology, Federico II University Hospital, 80131 Naples, Italy.
Giuseppe ServilloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
Marcello MocciaDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-2613-3090
Simona BonavitaDepartment of Advanced Medical and Surgical Sciences, II Clinic of Neurology, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-8561-9720
Massimo FilippiNeurology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Maria PetraccaDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
Vincenzo Brescia MorraDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
Roberta LanzilloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-6388-8180
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · ITOspedale Policlinico San Martino · ITVita-Salute San Raffaele University · ITSapienza University of Rome · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical disability impacts psychosocial wellbeing in people with multiple sclerosis. However, the role of physical activity in this context is still debated. By taking advantage of a previous survey, conducted online from 22 April to 7 May 2020, we performed a post-hoc analysis with the aim to assess the associations between disability, physical exercise, and mental health in multiple sclerosis. We retrieved the following data: (i) sociodemographic information, (ii) changes in lifestyle (including exercise), (iii) physical disability, as measured with the Patient-Determined Disease Steps scale, and (iv) anxiety feelings and depressive symptoms assessed via the items included in the Quality of Life in Neurological Disorders measurement system. Examination of the interaction plot showed that the effect of disability on depression, but not on anxious symptoms, was significant for all levels of physical exercise (low: b = 1.22, 95% C.I. 0.85, 1.58,

Indexed as

anxietyCOVID-19depressionmultiple sclerosisphysical exercise

Identifiers

PMID33809698
PMCPMC8002261
OpenAlexW3138601375

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.