ArticleInternational journal of molecular sciences2021
Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 63 citations in OpenAlex.
- Genome-wide variation landscape reveals temperature adaptation in Chinese indigenous cattle.Journal of animal science and biotechnology · 2026Article
- Distinct damage levels and transcriptional responses of lung in Hezuo pigs and Bama pigs during cold exposure.Animal bioscience · 2026Article
- Zebrafish as a Model Organism for Post-Traumatic Stress Disorder: Insights into Stress Mechanisms and Behavioral Assays.Biology · 2025Review
- Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis.Cellular & molecular biology letters · 2025Article
- Low-Temperature Stress-Induced Hepatic Injury in Darkbarbel Catfish (Antioxidants (Basel, Switzerland) · 2025Article
- Effects of Environmentally Friendly Aquaculture Chamber Coatings on Enzyme Activities, Histology, and Transcriptome in the Liver of Larimichthys crocea.Marine biotechnology (New York, N.Y.) · 2025Article
- Analysis of Differential Alternative Splicing in Largemouth Bass After High Temperature Exposure.Animals : an open access journal from MDPI · 2024Article
- Transcriptomic Characterization of Key Factors and Signaling Pathways for the Regeneration of Partially Hepatectomized Liver in Zebrafish.International journal of molecular sciences · 2024Article
- Rearing condition influences gene expression in postlarval American lobster (Homarus americanus).PloS one · 2024Article
- Secreted novel AID/APOBEC-like deaminase 1 (SNAD1) - a new important player in fish immunology.Frontiers in immunology · 2024Review
- The development of necroptosis: what we can learn.Cell stress & chaperones · 2023Review
- Transcriptome Analysis Revealed Potential Genes of Skeletal Muscle Thermogenesis in Mashen Pigs and Large White Pigs under Cold Stress.International journal of molecular sciences · 2023Article
- Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish.International journal of molecular sciences · 2023Article
- Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1.Antioxidants (Basel, Switzerland) · 2023Review
- Characterization of pig skeletal muscle transcriptomes in response to low temperature.Veterinary medicine and science · 2023Article
- Article
- A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.Nature communications · 2022Article
- Article
- Understanding the Function and Mechanism of Zebrafish Tmem39b in Regulating Cold Resistance.International journal of molecular sciences · 2022Article
- Mitochondria Dysfunction and Cell Apoptosis Limit Resistance of Nile Tilapia (Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Low temperature stress represents a major threat to the lives of both farmed and wild fish species. However, biological pathways determining the development of cold resistance in fish remain largely unknown. Zebrafish larvae at 96 hpf were exposed to lethal cold stress (10 °C) for different time periods to evaluate the adverse effects at organism, tissue and cell levels. Time series RNA sequencing (RNA-seq) experiments were performed to delineate the transcriptomic landscape of zebrafish larvae under cold stress and during the subsequent rewarming phase. The genes regulated by cold stress were characterized by progressively enhanced or decreased expression, whereas the genes associated with rewarming were characterized by rapid upregulation upon return to normal temperature (28 °C). Genes such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.