Evidence map›Paper›PMID 33809679›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Biological Activity Evaluation of Coumarin-3-Carboxamide Derivatives.

Weerachai Phutdhawong, Apiwat Chuenchid, Thongchai Taechowisan, Jitnapa Sirirak, Waya S Phutdhawong

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Synthesis, crystal structure and Hirshfeld surface analysis of phenyl-methanaminium 2-oxo-2Acta crystallographica. Section E, Crystallographic communications · 2026
    Article
  2. Syntheses and structures ofActa crystallographica. Section E, Crystallographic communications · 2026
    Article
  3. Review
  4. Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides.International journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Coumarin and Its Derivatives-Editorial.Molecules (Basel, Switzerland) · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weerachai PhutdhawongDepartment of Science, Faculty of Liberal Arts and Science, Kamphaeng Sean Campus, Kasetsart University, Nakhon Pathom 73140, Thailand.
Apiwat ChuenchidDepartment of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom 73000, Thailand.
Thongchai TaechowisanDepartment of Microbiology, Faculty of Science, Silpakorn University, Nakhon Pathom 73000, Thailand.
Jitnapa SirirakDepartment of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom 73000, Thailand.
Waya S PhutdhawongDepartment of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom 73000, Thailand.ORCID 0000-0003-1962-8693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel coumarin-3-carboxamide derivatives were designed and synthesized to evaluate their biological activities. The compounds showed little to no activity against gram-positive and gram-negative bacteria but specifically showed potential to inhibit the growth of cancer cells. In particular, among the tested compounds, 4-fluoro and 2,5-difluoro benzamide derivatives (

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsBenzamidesCell LineCell Line, TumorCoumarinsDoxorubicinGram-Negative BacteriaGram-Positive BacteriaHeLa CellsHep G2 CellsHumansMicrobial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsAntineoplastic AgentsbenzamideBenzamidescoumarinCoumarinsDoxorubicinantibacterial activityanticancer activitycoumarin3-carboxamidescoumarinspyranocoumarins

Identifiers

PMID33809679
PMCPMC8002271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.