Evidence map›Paper›PMID 33809630›Full record

ArticlePolymers2021

Fabrication and Characterization of Polyvinylpyrrolidone-Eggshell Membrane-Reduced Graphene Oxide Nanofibers for Tissue Engineering Applications.

Shahnaz Ghorbanzadeh Sheish, Rahmatollah Emadi, Mehdi Ahmadian, Sorour Sadeghzade, Fariborz Tavangarian

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. A comparison of several separation processes for eggshell membrane powder as a natural biomaterial for skin regeneration.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Avian Egg: A Multifaceted Biomaterial for Tissue Engineering.Industrial & engineering chemistry research · 2021
    Article
  11. Preparation ofPolymers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shahnaz Ghorbanzadeh SheishMaterials Engineering Group, Pardis College, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Rahmatollah EmadiDepartment of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Mehdi AhmadianDepartment of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Sorour SadeghzadeDepartment of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.ORCID 0000-0002-7034-4808
Fariborz TavangarianMechanical Engineering Program, School of Science, Engineering and Technology, Penn State Harrisburg, Middletown, PA 17057, USA.
Isfahan University of Technology · IRPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the best methods to prevent wound infection and speed up wound healing is wound dressing based on nanofiber-polymer scaffolds, which have acceptable antimicrobial performance and appropriate skin regeneration capabilities. In this paper, the electrospinning method was applied to synthesize the polyvinylpyrrolidone-acrylic acid hydrogel (PVPA)-eggshell membrane (ESM)-reduced graphene oxide (rGO) nanosheets nanocomposite dressings with different reduced graphene oxide contents (0, 0.5, 1, and 2 wt.%). Thus, smooth nanofibers were fabricated, including a high amount of rGO, which reduced the fiber diameter. Based on the results, rGO played an important role in water impermeability. The results showed that by increasing the rGO concentration from 0.5 to 2 wt%, the contact angle value increased persistently. Results showed that compared to PVPA-ESM, the mechanical strength and strain of PVPA-ESM/1 wt% rGO significantly enhanced 28% and 23%, respectively. Incorporation of 1 wt% rGO enhanced swelling ratio from 875% for PVPA-ESM to 1235% after 420 min, while increasing the rGO to 2 wt% increased the degradation rate of the composites. According to the in vitro cell culture studies, PVPA-ESM wound dressings with 0.5-1 wt% rGO content enhanced PC12 cell viability compared to the wound dressings without rGO nanosheets. Generally, rGO-loaded PVPA-ESM nanofiber wound dressing can be considered as a potential candidate to be used in skin regeneration applications.

Indexed as

biocompatibilityeggshell membraneelectrospinninggraphene oxidepolyvinylpyrrolidonewound dressing

Identifiers

PMID33809630
PMCPMC8002296
OpenAlexW3138874016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.