ArticleAntioxidants (Basel, Switzerland)2021
Old Plant, New Possibilities: Wild Bilberry (
Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Comparative Effects of Fruit-Derived Pectins on the Stability and Antioxidant Activity of Bilberry Anthocyanin-Pectin Complexes.Foods (Basel, Switzerland) · 2026Article
- A Review of Major Compounds in Bilberry (Nutrients · 2026Review
- Skin Performance of Innovative NaDES-Based Gels: In Vivo Evaluation of Anti-Irritation Potential and Short-Term Efficacy.Gels (Basel, Switzerland) · 2025Article
- Preliminary Analysis of Bilberry NaDES Extracts as Versatile Active Ingredients of Natural Dermocosmetic Products: In Vitro Evaluation of Anti-Tyrosinase, Anti-Hyaluronidase, Anti-Collagenase, and UV Protective Properties.Plants (Basel, Switzerland) · 2025Article
- In Vitro Evaluation of Antidiabetic, Antioxidant, and Anticholinergic Properties of Different Parts of Bilberry (Food science & nutrition · 2025Article
- Article
- Unraveling Skin Carcinoma: A Comprehensive Examination of Diagnosis, Treatment Strategies, and Emerging Therapeutic Avenues in Skin Cancer Management.Pharmaceutical nanotechnology · 2025Review
- Review
- Liposomal Encapsulation of Ascorbyl Palmitate: Influence on Skin Performance.Pharmaceutics · 2024Article
- Design of Scaffolds Based on Zinc-Modified Marine Collagen and Bilberry Leaves Extract-Loaded Silica Nanoparticles as Wound Dressings.International journal of nanomedicine · 2024Article
- Review
- Medicinal Plants of the Flora of Kazakhstan Used in the Treatment of Skin Diseases.Molecules (Basel, Switzerland) · 2023Review
- Establishment of a Sonotrode Extraction Method and Evaluation of the Antioxidant, Antimicrobial and Anticancer Potential of an OptimizedFoods (Basel, Switzerland) · 2023Article
- Comprehensive Analysis of Antioxidant and Hepatoprotective Properties ofAntioxidants (Basel, Switzerland) · 2023Article
- An Updated Systematic Review ofPharmaceutics · 2022Review
- Caucasian Blueberry: Comparative Study of Phenolic Compounds and Neuroprotective and Antioxidant Potential of Vaccinium myrtillus and Vaccinium arctostaphylos LeavesLife (Basel, Switzerland) · 2022Article
- Conventional vs. Green Extraction Using Natural Deep Eutectic Solvents-Differences in the Composition of Soluble Unbound Phenolic Compounds and Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2022Article
- Spectrum-effect relationship between ultra-high-performance liquid chromatography fingerprints and antioxidant activities ofFood science & nutrition · 2022Article
- Bilberries: Curative and Miraculous - A Review on Bioactive Constituents and Clinical Research.Frontiers in pharmacology · 2022Review
- Intensification Technologies to Efficiently Extract Antioxidants from Agro-Food Residues.Antioxidants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
Bilberry represents a valuable source of antioxidant substances responsible for its application for the treatment of different conditions (such as inflammation, cardiovascular disease, cancer, diabetes, and different age-related diseases) associated with increased oxidative stress. As oxidative stress might cause skin impairments, we aim to evaluate a topical preparation containing bilberry leaves extract and bilberry seeds oil, obtained as a byproduct of the food industry. To obtain the extracts, the conventional maceration technique for leaves, and supercritical carbon dioxide extraction for seeds were employed. The chemical profile of both actives was achieved by HPLC and GC methods, revealing the presence of phenolic acids (chlorogenic being the most abundant), flavonoids (isoquercetin in the highest amount), and resveratrol in leaves extract, while in seeds oil the essential ω-3 and ω-6 fatty acids were determined in favorable ratio, almost being 1. Antioxidant potential of the wild bilberry extract and seed oil was evaluated using in vitro DPPH and FRAP assays. Finally, effects of the oil-in-water creams with mentioned wild bilberry isolates on the skin were investigated in an in vivo study conducted on healthy human volunteers, revealing the significant beneficial effects when topically applied.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.