Evidence map›Paper›PMID 33809543›Full record

ArticleCancers2021

The Extracellular Small Leucine-Rich Proteoglycan Biglycan Is a Key Player in Gastric Cancer Aggressiveness.

Filipe Pinto, Liliana Santos-Ferreira, Marta T Pinto, Catarina Gomes, Celso A Reis

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Biglycan stimulates retinal pathological angiogenesis via up-regulation of CXCL12 expression in pericytes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
  4. Biglycan promotes proliferation and metastasis of ovarian cancer.International journal of clinical and experimental pathology · 2025
    Article
  5. Article
  6. Article
  7. Biomimetic proteoglycans as a tool to engineer the structure and mechanics of porcine bioprosthetic heart valves.Journal of biomedical materials research. Part B, Applied biomaterials · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Small Leucine-Rich Proteoglycans (SLRPs) in the Retina.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Filipe PintoInstituto de Investigação e Inovação em Saúde (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-2330-9863
Liliana Santos-FerreiraInstituto de Investigação e Inovação em Saúde (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-1937-1904
Marta T PintoInstituto de Investigação e Inovação em Saúde (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-8521-2904
Catarina GomesInstituto de Investigação e Inovação em Saúde (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0352-6783
Celso A ReisInstituto de Investigação e Inovação em Saúde (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0286-6639
Universidade do Porto · PT

Funding

Fundação para a Ciência e a Tecnologia PTDC/BBB-EBI/0567/2014Fundação para a Ciência e a Tecnologia PTDC/MED-QUI/29780/2017Fundação para a Ciência e a Tecnologia SFRH/BPD/115730/2016Programa Operacional Temático Factores de Competitividade POCI-01-0145-FEDER-007274Programa Operacional Temático Factores de Competitividade POCI-01-0145-FEDER-016585Programa Operacional Temático Factores de Competitividade POCI-01-0145-FEDER-029780
6 · The paper itself

Abstract

Biglycan (

Indexed as

biglycancancer aggressivenessgastric cancerprognostic biomarkersmall leucine-rich proteoglycan

Identifiers

PMID33809543
PMCPMC8001774
OpenAlexW3139118971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.