Evidence map›Paper›PMID 33809461›Full record

ArticleNutrients2021

Serum Selenium Level Predicts 10-Year Survival after Breast Cancer.

Marek Szwiec, Wojciech Marciniak, Róża Derkacz, Tomasz Huzarski, Jacek Gronwald, Cezary Cybulski, Tadeusz Dębniak, Anna Jakubowska, Marcin Lener, Michał Falco and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Observational
  11. Micronutrient Status and Breast Cancer: A Narrative Review.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Marek SzwiecDepartment of Surgery and Oncology, University of Zielona Góra, Zyty 28, 65-046 Zielona Góra, Poland.ORCID 0000-0001-6981-6356
Wojciech MarciniakRead-Gene S.A., 72-003 Grzepnica, Poland.ORCID 0000-0001-7270-0063
Róża DerkaczRead-Gene S.A., 72-003 Grzepnica, Poland.ORCID 0000-0002-2904-5259
Tomasz HuzarskiDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.ORCID 0000-0003-3857-4854
Jacek GronwaldDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.ORCID 0000-0002-3643-2871
Cezary CybulskiDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.ORCID 0000-0002-2819-3057
Tadeusz DębniakDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.
Anna JakubowskaDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.ORCID 0000-0002-5650-0501
Marcin LenerDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.
Michał FalcoRegional Oncology Centre, 71-730 Szczecin, Poland.
Józef KładnyDepartment of General and Oncological Surgery, Pomeranian Medical University, 71-252 Szczecin, Poland.
Piotr BaszukDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 71-252 Szczecin, Poland.ORCID 0000-0002-0676-2597
Jerzy DuszyńskiNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
Joanne KotsopoulosWomen's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON M5G 1N8, Canada.
Steven A NarodWomen's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON M5G 1N8, Canada.
Jan LubińskiRead-Gene S.A., 72-003 Grzepnica, Poland.
International Hereditary Cancer Center · PLRead-Gene (Poland) · PLUniversity of Toronto · CAInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLPomeranian Medical University · PLUniversity of Zielona Góra · PL

Funding

Narodowe Centrum Badań i Rozwoju INNOMED/I/16/ NCBR/2014
6 · The paper itself

Abstract

In a recent prospective study, we reported an association between a low serum selenium level and five-year survival among breast cancer patients. We now have updated the cohort to include 10-year survival rates. A blood sample was obtained from 538 women diagnosed with first primary invasive breast cancer between 2008 and 2015 in the region of Szczecin, Poland. Blood was collected before initiation of treatment. Serum selenium levels were quantified by mass spectroscopy. Each patient was assigned to one of four quartiles based on the distribution of serum selenium levels in the whole cohort. Patients were followed from diagnosis until death or last known alive (mean follow-up 7.9 years). The 10-year actuarial cumulative survival was 65.1% for women in the lowest quartile of serum selenium, compared to 86.7% for women in the highest quartile (

Indexed as

AdultAgedAged, 80 and overAge FactorsBreast NeoplasmsFemaleHumansMiddle AgedRisk FactorsSeleniumSurvival AnalysisTime FactorsSeleniumbreast cancermortalityselenium

Identifiers

PMID33809461
PMCPMC7998294
OpenAlexW3135942735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.