Evidence map›Paper›PMID 33809454›Full record

ArticleMicroorganisms2021

Loop-Mediated Isothermal Amplification Allows Rapid, Simple and Accurate Molecular Diagnosis of Human Cutaneous and Visceral Leishmaniasis Caused by

Ana Victoria Ibarra-Meneses, Carmen Chicharro, Carmen Sánchez, Emilia García, Sheila Ortega, Joseph Mathu Ndung'u, Javier Moreno, Israel Cruz, Eugenia Carrillo

Abstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Molecular Detection ofAdvanced biomedical research · 2026
    Article
  6. Leishmaniasis.Nature reviews. Disease primers · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana Victoria Ibarra-MenesesWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Carmen ChicharroWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Carmen SánchezWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Emilia GarcíaWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Sheila OrtegaWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Joseph Mathu Ndung'uFoundation for Innovative New Diagnostics, 1202 Geneva, Switzerland.
Javier MorenoWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Israel CruzFoundation for Innovative New Diagnostics, 1202 Geneva, Switzerland.ORCID 0000-0002-2200-2360
Eugenia CarrilloWHO Collaborating Centre for Leishmaniasis, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.ORCID 0000-0002-7869-7915

Funding

Federal Ministry of Education and Research, Germany, and the Ministry of Foreign Affairs, Government of the Netherlands, through FIND. RD16CIII/0003/0002 from the Red de Investigación Cooperativa de Enfermedades Tropicales, Subprograma RETICS del Plan Est RD16CIII/0003/0002
6 · The paper itself

Abstract

Loop-mediated isothermal amplification allows the rapid, sensitive and specific amplification of DNA without complex and expensive equipment. We compared the diagnostic performance of Loopamp™

Indexed as

cutaneous leishmaniasisdiagnosisLAMPLeishmania infantumLoopamploop-mediated isothermal amplificationPCRvisceral leishmaniasis

Identifiers

PMID33809454
PMCPMC7999953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.