Evidence map›Paper›PMID 33809168›Full record

ArticleInternational journal of environmental research and public health2021

Universal Access to Xpert MTB/RIF Testing for Diagnosis of Tuberculosis in Uzbekistan: How Well Are We Doing?

Laziz Turaev, Ajay Kumar, Dilyara Nabirova, Sevak Alaverdyan, Nargiza Parpieva, Barno Abdusamatova

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Use of rapid molecular TB diagnostics for incarcerated people in Brazil.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laziz TuraevNational Reference Laboratory, Tashkent 100086, Uzbekistan.ORCID 0000-0002-8696-1851
Ajay KumarInternational Union Against Tuberculosis and Lung Disease, South-East Asia Office, New Delhi 110016, India.ORCID 0000-0003-1011-8531
Dilyara NabirovaUnited States Centers for Disease Control and Prevention, Central Asia Region, Almaty A25T0A1, Kazakhstan.ORCID 0000-0002-0314-2202
Sevak AlaverdyanBielefeld Graduate School of Economics and Management (BiGSEM), Bielefeld University, Universitätsstraße, 33615 Bielefeld, Germany.
Nargiza ParpievaNational Tuberculosis Programme, Ministry of Health, Tashkent 100086, Uzbekistan.
Barno AbdusamatovaMinistry of Health, Tashkent 100086, Uzbekistan.

Funding

World Health Organization N/A
6 · The paper itself

Abstract

As per national guidelines in Uzbekistan, all presumptive tuberculosis patients should be tested using the Xpert MTB/RIF assay for diagnosing tuberculosis. There is no published evidence how well this is being implemented. In this paper, we report on the Xpert coverage among presumptive tuberculosis patients in 2018 and 2019, factors associated with non-testing and delays involved. Analysis of national aggregate data indicated that Xpert testing increased from 24% in 2018 to 46% in 2019, with variation among the regions: 21% in Tashkent region to 100% in Karakalpakstan. In a cohort (January-March 2019) constituted of 40 randomly selected health facilities in Tashkent city and Bukhara region, there were 1940 patients of whom 832 (43%, 95% confidence interval (CI): 41-45%) were not Xpert-tested. Non-testing was significantly higher in Bukhara region (73%) compared to Tashkent city (28%). In multivariable analysis, patient's age, distance between primary health centre (PHC) and Xpert laboratory, diagnostic capacity and site of PHC were associated with non-testing. The median (interquartile range) duration from date of initial visit to PHC to receiving results was 1 (1-2) day in Tashkent city compared to 3 (1-6) days in Bukhara region (

Indexed as

Mycobacterium tuberculosisTuberculosisTuberculosis, PulmonaryHumansRifampinSensitivity and SpecificitySputumUzbekistanRifampincentral Asiamissing casesnucleic acid amplification testsoperational researchpolymerase chain reactionpre-diagnosis attritionrapid molecular diagnosticsSORT IT

Identifiers

PMID33809168
PMCPMC8000337

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.