Evidence map›Paper›PMID 33808969›Full record

ArticleMolecules (Basel, Switzerland)2021

Anticancer Potential of Damnacanthal and Nordamnacanthal from

Saiful Yazan Latifah, Banulata Gopalsamy, Raha Abdul Rahim, Abdul Manaf Ali, Nordin Haji Lajis

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Extracts ofMolecules (Basel, Switzerland) · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saiful Yazan LatifahDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Banulata GopalsamyDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Raha Abdul RahimDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Abdul Manaf AliFaculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin (UniSZA), Kuala 20300, Terengganu, Malaysia.
Nordin Haji LajisLaboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Universiti Putra Malaysia · MYSultan Zainal Abidin University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study reports on the cytotoxic properties of nordamnacanthal and damnacanthal, isolated from roots of

methodsMTT assay, DNA fragmentation, ELISA and cell cycle analysis were carried out.

resultsNordamnacanthal and damnacanthal at IC

conclusionDamnacanthal and nordamnacanthal have anticancer properties, and could act as potential treatment for T-lymphoblastic leukemia.

Indexed as

AldehydesAnthraquinonesAntineoplastic Agents, PhytogenicApoptosisCell CycleCell Line, TumorCell SurvivalDNA FragmentationEndodeoxyribonucleasesHumansMorindaPlant RootsPlants, MedicinalPrecursor T-Cell Lymphoblastic Leukemia-LymphomaAldehydesAnthraquinonesAntineoplastic Agents, Phytogeniccalcium magnesium dependent endodeoxyribonucleasedamnacanthalEndodeoxyribonucleasesnordamnacanthalanticancerapoptosisCEM-SScytotoxicdamnacanthalG0/G1 arrestMg2+/Ca2+-dependent endonucleasenordamnacanthal

Identifiers

PMID33808969
PMCPMC7998966
OpenAlexW3137308624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.