Evidence map›Paper›PMID 33808930›Full record

ArticleMicroorganisms2021

In Silico Prediction and Analysis of Unusual Lantibiotic Resistance Operons in the Genus

Oliver Goldbeck, Dominik Weixler, Bernhard J Eikmanns, Christian U Riedel

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Oliver GoldbeckInstitute of Microbiology and Biotechnology, Ulm University, 89081 Ulm, Germany.
Dominik WeixlerInstitute of Microbiology and Biotechnology, Ulm University, 89081 Ulm, Germany.
Bernhard J EikmannsInstitute of Microbiology and Biotechnology, Ulm University, 89081 Ulm, Germany.
Christian U RiedelInstitute of Microbiology and Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-7134-7085
Universität Ulm · DE

Funding

Bio-Based Industries Joint Undertaking 790507
6 · The paper itself

Abstract

Post-translationally modified, (methyl-)lanthionine-containing peptides are produced by several Gram-positive bacteria. These so-called lantibiotics have potent activity against various bacterial pathogens including multidrug-resistant strains and are thus discussed as alternatives to antibiotics. Several naturally occurring mechanisms of resistance against lantibiotics have been described for bacteria, including cell envelope modifications, ABC-transporters, lipoproteins and peptidases.

Indexed as

antimicrobial peptidesbacteriocinsCorynebacteriumin silico analysislantibioticsnisinresistance

Identifiers

PMID33808930
PMCPMC8003753
OpenAlexW3138345182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.