Evidence map›Paper›PMID 33808898›Full record

ArticleInternational journal of molecular sciences2021

Tailored-Made Polydopamine Nanoparticles to Induce Ferroptosis in Breast Cancer Cells in Combination with Chemotherapy.

Celia Nieto, Milena A Vega, Eva M Martín Del Valle

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
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  8. Review
  9. Nanomaterials in Cancer Diagnosis and Therapy.International journal of molecular sciences · 2022
    Article
  10. Article
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  12. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Celia NietoDepartamento de Ingeniería Química y Textil, Facultad de Ciencias Químicas, Universidad de Salamanca, 37008 Salamanca, Spain.ORCID 0000-0001-5484-5816
Milena A VegaDepartamento de Ingeniería Química y Textil, Facultad de Ciencias Químicas, Universidad de Salamanca, 37008 Salamanca, Spain.ORCID 0000-0002-4296-0478
Eva M Martín Del ValleDepartamento de Ingeniería Química y Textil, Facultad de Ciencias Químicas, Universidad de Salamanca, 37008 Salamanca, Spain.ORCID 0000-0003-3506-2546
Universidad de Salamanca · ES

Funding

Ministerio de Ciencia, Innovación y Universidades PID2019-1088994R-100
6 · The paper itself

Abstract

Ferroptosis is gaining followers as mechanism of selective killing cancer cells in a non-apoptotic manner, and novel nanosystems capable of inducing this iron-dependent death are being increasingly developed. Among them, polydopamine nanoparticles (PDA NPs) are arousing interest, since they have great capability of chelating iron. In this work, PDA NPs were loaded with Fe

Indexed as

AnimalsAntineoplastic AgentsBreast NeoplasmsCalciumCell Line, TumorCell SurvivalDose-Response Relationship, DrugDrug SynergismFemaleFerroptosisHumansIndolesIronMiceNanoparticlesPolymersAntineoplastic AgentsCalciumIndolesIronpolydopaminePolymersReactive Oxygen Speciesbreast cancerdoxorubicinferroptosisironpolydopamine nanoparticlesreactive oxygen species

Identifiers

PMID33808898
PMCPMC8003616
OpenAlexW3137793535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.