Evidence map›Paper›PMID 33808856›Full record

ArticleCancers2021

Age-Related Biology of Early-Stage Operable Breast Cancer and Its Impact on Clinical Outcome.

Binafsha M Syed, Andrew R Green, Emad A Rakha, David A L Morgan, Ian O Ellis, Kwok-Leung Cheung

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Does age matter?-the significance of age in breast cancer.Annals of translational medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Binafsha M SyedSchool of Medicine, University of Nottingham, Derby DE22 3DT, UK.
Andrew R GreenSchool of Medicine, University of Nottingham, Derby DE22 3DT, UK.ORCID 0000-0002-0488-5913
Emad A RakhaSchool of Medicine, University of Nottingham, Derby DE22 3DT, UK.
David A L MorganDepartment of Oncology, Nottingham University Hospitals, Nottingham NG5 1PB, UK.ORCID 0000-0002-2291-1740
Ian O EllisSchool of Medicine, University of Nottingham, Derby DE22 3DT, UK.
Kwok-Leung CheungSchool of Medicine, University of Nottingham, Derby DE22 3DT, UK.ORCID 0000-0003-2973-0755
University of Nottingham · GBLiaquat University of Medical & Health Sciences · PKNottingham University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As age advances, breast cancer (BC) tends to change its biological characteristics. This study aimed to explore the natural progression of such changes. The study included 2383 women with clinically T0-2N0-1M0 BC, managed by primary surgery and optimal adjuvant therapy in a dedicated BC facility. Tissue micro-arrays were constructed from their surgical specimens and indirect immunohistochemistry was used for analysis of a large panel (

Indexed as

biologybreast cancerolder women

Identifiers

PMID33808856
PMCPMC8003777
OpenAlexW3137581816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.