Evidence map›Paper›PMID 33808823›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Nanonutraceuticals: The New Frontier of Supplementary Food.

Donatella Paolino, Antonia Mancuso, Maria Chiara Cristiano, Francesca Froiio, Narimane Lammari, Christian Celia, Massimo Fresta

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Chemical characterization and encapsulation ofFrontiers in pharmacology · 2025
    Article
  6. A Lupin (International journal of molecular sciences · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Nutraceutical Concepts and Dextrin-Based Delivery Systems.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Nanonutraceuticals Delivery.Nanomaterials (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Donatella PaolinoDepartment of Experimental and Clinical Medicine, University of Catanzaro "Magna Graecia", Viale Europa s.n.c., I-88100 Catanzaro, Italy.ORCID 0000-0002-5223-9879
Antonia MancusoDepartment of Health Sciences, University of Catanzaro "Magna Graecia", Viale Europa s.n.c., I-88100 Catanzaro, Italy.ORCID 0000-0002-0915-8643
Maria Chiara CristianoDepartment of Experimental and Clinical Medicine, University of Catanzaro "Magna Graecia", Viale Europa s.n.c., I-88100 Catanzaro, Italy.ORCID 0000-0002-5510-7599
Francesca FroiioDepartment of Experimental and Clinical Medicine, University of Catanzaro "Magna Graecia", Viale Europa s.n.c., I-88100 Catanzaro, Italy.
Narimane LammariEnvironmental Process Engineering Laboratory, University Constantine 3, Salah Boubnider, 25000 Constantine, Algeria.
Christian CeliaDepartment of Pharmacy, University of Chieti-Pescara "G. d'Annunzio", Via dei Vestini 31, I-66100 Chieti, Italy.ORCID 0000-0002-0590-5429
Massimo FrestaDepartment of Health Sciences, University of Catanzaro "Magna Graecia", Viale Europa s.n.c., I-88100 Catanzaro, Italy.ORCID 0000-0001-8062-817X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few decades, the combination between nanotechnology and nutraceutics has gained the attention of several research groups. Nutraceuticals are considered as active compounds, abundant in natural products, showing beneficial effects on human health. Unfortunately, the uses, and consequently the health benefits, of many nutraceutical products are limited by their unsuitable chemico-physical features. For example, many nutraceuticals are characterized by low water solubility, low stability and high susceptibility to light and oxygen, poor absorption and potential chemical modifications after their administration. Based on the potential efficacy of nutraceuticals and on their limiting features, nanotechnology could be considered a revolutionary innovation in empowering the beneficial properties of nutraceuticals on human health, thus enhancing their efficacy in several diseases. For this reason, nanotechnology could represent a new frontier in supplementary food. In this review, the most recent nanotechnological approaches are discussed, focusing on their ability to improve the bioavailability of the most common nutraceuticals, providing an overview regarding both the advantages and the possible limitations of the use of several nanodelivery systems. In fact, although the efficacy of smart nanocarriers in improving health benefits deriving from nutraceuticals has been widely demonstrated, the conflicting opinions on the mechanism of action of some nanosystems still reduce their applicability in the therapeutic field.

Indexed as

health benefitsnanocarriersnutraceuticalssmart deliverysupplementary food

Identifiers

PMID33808823
PMCPMC8003744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.