ArticleJournal of personalized medicine2021
Expansion of CD4 T Lymphocytes Expressing Interleukin 17 and Tumor Necrosis Factor in Patients with Major Depressive Disorder.
Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06158152 (A Randomized, Double-blind, Placebo-controlled Pilot Study to Evaluate the Systemic Effect on Immunoinflammatory and Metabolic Status of an Oral Supplementation With AM3 in Patients With Metabolic Syndrome.), which is not on this map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized, Double-blind, Placebo-controlled Pilot Study to Evaluate the Systemic Effect on Immunoinflammatory and Metabolic Status of an Oral Supplementation With AM3 in Patients With Metabolic Syndrome.
Who cites it
32 citing papers in PubMed, 53 citations in OpenAlex.
- The Impact ofNutrients · 2025Trial
- Huaiqihuang Alleviates Imiquimod-Induced Psoriasis-Like Skin Lesions and Depressive-Like Behaviors in Mice.Current medical science · 2026Article
- Potential Shared Immunometabolic Signatures Between Familial Hypercholesterolemia and Major Depressive Disorder: Integrative Transcriptomic Analysis, Mendelian Randomization, and Clinical Validation.International journal of molecular sciences · 2026Article
- Association of circulating immune cell phenotypes and peripheral inflammatory biomarkers with depressive symptoms in the Framingham Heart Study.Psychoneuroendocrinology · 2026Article
- Re-Examination of Inflammation in Major Depressive Disorder: Bridging Systemic and Neuroinflammatory Insights.Biomolecules · 2025Review
- High dietary live microbe intake associated with reduced depressive symptoms in gastrointestinal disease patients: findings from a cross-sectional study.Nutrition & metabolism · 2025Article
- Flow-cytometric analysis of immune cell populations in patients with depression: relationship with depression severity and electroconvulsive therapy therapeutic outcomes.Frontiers in cellular neuroscience · 2025Article
- Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies.Frontiers in neuroscience · 2025Review
- Understanding immune system dysfunction and its context in mood disorders: psychoneuroimmunoendocrinology and clinical interventions.Military Medical Research · 2024Review
- Review
- Mood and microbes: a comprehensive review of intestinal microbiota's impact on depression.Frontiers in psychiatry · 2024Review
- Patients with Chronic Spinal Cord Injury Display a Progressive Alteration over the Years of the Activation Stages of the T Lymphocyte Compartment.International journal of molecular sciences · 2023Article
- Review
- A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities.Military Medical Research · 2023Review
- Fenugreek and Its Effects on Muscle Performance: A Systematic Review.Journal of personalized medicine · 2023Review
- A Review: Integrative Perspectives on the Features and Clinical Management of Psychotic Episodes in Pregnancy.Journal of clinical medicine · 2023Review
- From the immune system to mood disorders especially induced byFrontiers in cellular and infection microbiology · 2023Review
- Selected Biomarkers of Depression: What Are the Effects of Cytokines and Inflammation?International journal of molecular sciences · 2022Review
- Depression Pathophysiology: Astrocyte Mitochondrial Melatonergic Pathway as Crucial Hub.International journal of molecular sciences · 2022Review
- Innate lymphoid cells in depression: Current status and perspectives.Biomarkers in neuropsychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe have investigated the distribution of the Th1, Th2 and Th17 subsets in circulating CD4
methodsThirty MDD patients and 30 healthy controls were studied. The counts of circulating CD4
resultsMDD patients had normal counts of CD4 LIMITATIONS: the cross-sectional nature of the study could be considered a limitation.
conclusionsMDD patients have abnormal circulating CD4
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.