Evidence map›Paper›PMID 33808678›Full record

ArticleJournal of clinical medicine2021

Five-Year Comparative Efficacy of Everolimus-Eluting vs. Resolute Zotarolimus-Eluting Stents in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

Endrin Koni, Wojciech Wanha, Jakub Ratajczak, Zhongheng Zhang, Przemysław Podhajski, Rita L. Musci, Giuseppe M. Sangiorgi, Maciej Kaźmierski, Antonio Buffon, Jacek Kubica and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Endrin KoniDepartment of Interventional Cardiology, Santa Corona Hospital, 17027 Pietra Ligure, Italy.
Wojciech WanhaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40635 Katowice, Poland.ORCID 0000-0003-1220-9496
Jakub RatajczakDepartment of Cardiology and Internal Medicine, Nicolaus Copernicus University, 87100 Bydgoszcz, Poland.
Zhongheng ZhangDepartment of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.ORCID 0000-0002-2336-5323
Przemysław PodhajskiDepartment of Cardiology and Internal Medicine, Nicolaus Copernicus University, 87100 Bydgoszcz, Poland.
Rita L. MusciDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00173 Rome, Italy.
Giuseppe M. SangiorgiCardiac Cath Lab, Department of Cardiology, San Gaudenzio Clinic, 28100 Novara, Italy.ORCID 0000-0001-5862-1967
Maciej KaźmierskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40635 Katowice, Poland.
Antonio BuffonInstitute of Cardiology, Catholic University of the Sacred Heart Rome, 00168 Rome, Italy.
Jacek KubicaDepartment of Cardiology and Internal Medicine, Nicolaus Copernicus University, 87100 Bydgoszcz, Poland.
Wojciech WojakowskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40635 Katowice, Poland.ORCID 0000-0002-3681-5207
Eliano P. NavareseSIRIO MEDICINE Research Network, 85094 Bydgoszcz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among drug-eluting stents (DESs), the durable polymer everolimus-eluting stent (EES) and resolute zotarolimus-eluting stent (R-ZES) are widely used in clinical practice and have contributed to improve the outcomes of patients undergoing percutaneous coronary intervention (PCI). Few studies addressed their long-term comparative performance in patients with acute coronary syndrome (ACS). We aimed to investigate the 5 year comparative efficacy of EES and R-ZES in ACS. We queried ACTION-ACS, a large-scale database of ACS patients undergoing PCI. The treatment groups were analyzed using propensity score matching. The primary endpoint was a composite of mortality, myocardial infarction (MI), stroke, repeat PCI, and definite or probable stent thrombosis, which was addressed at the five-year follow-up. A total of 3497 matched patients were analyzed. Compared with R-ZES, a significant reduction in the primary endpoint at 5 years was observed in patients treated with EES (hazard ratio (HR) [95%CI] = 0.62 [0.54-0.71],

Indexed as

acute coronary syndromeeverolimus-eluting stentresolute zotarolimus-eluting stent

Identifiers

PMID33808678
PMCPMC8003362

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.