Evidence map›Paper›PMID 33808650›Full record

ArticleMolecules (Basel, Switzerland)2021

Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.

Xin Luo, Qiangqiang Deng, Yaru Xue, Tianwei Zhang, Zhitao Wu, Huige Peng, Lijiang Xuan, Guoyu Pan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Frontiers in pharmacology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xin LuoState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Qiangqiang DengState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Yaru XueState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Tianwei ZhangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Zhitao WuSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210033, China.
Huige PengState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Lijiang XuanState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.ORCID 0000-0002-0593-3921
Guoyu PanState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 501 Haike Road, Shanghai 201203, China.
Shanghai Institute of Materia Medica · CNNanjing University of Chinese Medicine · CN

Funding

China Postdoctoral Science Foundation 2019M651623International Partnership Program of Chinese Academy of Sciences 153631KYSB20160004National Natural Science Foundation of China 81872927the Independent Deployment Program of the Institute of Pharmaceutical Innovation of the Chinese Academy of Sciences CASIMM0120184005the 'Organ Reconstruction and Manufacturing' Strategic Priority Research Program of the Chi-nese Academy of Sciences XDA16020205
6 · The paper itself

Abstract

Pulmonary fibrosis is a severe and irreversible interstitial pulmonary disease with high mortality and few treatments. Magnesium lithospermate B (MLB) is a hydrosoluble component of

Indexed as

Pulmonary FibrosisAnimalsBleomycinDisease Models, AnimalDrugs, Chinese HerbalMaleMiceReceptor, Transforming Growth Factor-beta Type ISignal TransductionSmad ProteinsBleomycinDrugs, Chinese Herballithospermate BReceptor, Transforming Growth Factor-beta Type ISmad ProteinsTgfbr1 protein, mousebleomycinmagnesium lithospermate Bpulmonary fibrosisSmad signalingtransforming growth factor-beta

Identifiers

PMID33808650
PMCPMC8003516
OpenAlexW3137773399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.