Evidence map›Paper›PMID 33808643›Full record

ArticleBiomolecules2021

QSAR-Based Virtual Screening of Natural Products Database for Identification of Potent Antimalarial Hits.

Letícia Tiburcio Ferreira, Joyce V B Borba, José Teófilo Moreira-Filho, Aline Rimoldi, Carolina Horta Andrade, Fabio Trindade Maranhão Costa

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lead/Drug Discovery from Natural Resources.Molecules (Basel, Switzerland) · 2022
    Review
  9. Antimalarial Natural Products.Progress in the chemistry of organic natural products · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Letícia Tiburcio FerreiraLaboratory of Tropical Diseases Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, SP 13083-864, Brazil.ORCID 0000-0002-5590-3878
Joyce V B BorbaLaboratory of Tropical Diseases Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, SP 13083-864, Brazil.ORCID 0000-0002-2663-5173
José Teófilo Moreira-FilhoLaboratory of Molecular Modeling and Drug Design, LabMol, Faculty of Pharmacy, Federal University of Goiás, Goiânia, GO 74605-170, Brazil.
Aline RimoldiLaboratory of Tropical Diseases Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, SP 13083-864, Brazil.
Carolina Horta AndradeLaboratory of Molecular Modeling and Drug Design, LabMol, Faculty of Pharmacy, Federal University of Goiás, Goiânia, GO 74605-170, Brazil.
Fabio Trindade Maranhão CostaLaboratory of Tropical Diseases Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, SP 13083-864, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Goiás · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/18611-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/02171-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/21854-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/02158-4
6 · The paper itself

Abstract

With about 400,000 annual deaths worldwide, malaria remains a public health burden in tropical and subtropical areas, especially in low-income countries. Selection of drug-resistant

Indexed as

AntimalarialsArtemisininsBiological ProductsPlasmodium falciparumQuantitative Structure-Activity RelationshipQuinineAntimalarialsartemisininArtemisininsBiological ProductsQuinineADMEexperimental validationnatural productsPlasmodium falciparumQSARvirtual screening

Identifiers

PMID33808643
PMCPMC8003391
OpenAlexW3137440015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.