Evidence map›Paper›PMID 33808622›Full record

ArticleNutrients2021

Selection of Gut-Resistant Bacteria and Construction of Microbial Consortia for Improving Gluten Digestion under Simulated Gastrointestinal Conditions.

Maria De Angelis, Sonya Siragusa, Mirco Vacca, Raffaella Di Cagno, Fernanda Cristofori, Michael Schwarm, Stefan Pelzer, Monika Flügel, Bodo Speckmann, Ruggiero Francavilla and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05798689 (Novel Probiotic Preparation With Gluten Degrading Activity and Gut Microbiota Modulating Effect), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05798689 nacompletednot on this map

Novel Probiotic Preparation With Gluten Degrading Activity and Gut Microbiota Modulating Effect

TypeinterventionalSponsorFree University of Bozen-BolzanoRan2020 to 2021Enrolled70ConditionsProbioticsArmsProbiotic administration and gluten, Placebo administration and gluten
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Novel probiotic preparation withMicrobiology spectrum · 2024
    Trial
  2. Carrot flour-enriched pasta withFrontiers in nutrition · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Frontiers in nutrition · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Maria De AngelisDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0002-2010-884X
Sonya SiragusaDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, 70126 Bari, Italy.
Mirco VaccaDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0003-0813-169X
Raffaella Di CagnoFaculty of Science and Technology, Free University of Bozen, 39100 Bolzano, Italy.
Fernanda CristoforiInterdisciplinary Department of Medicine-Pediatric Section, University of Bari Aldo Moro, Ospedale Pediatrico Giovanni XXIII, 70125 Bari, Italy.
Michael SchwarmEvonik Operations GmbH, 63457 Hanau-Wolfgang, Germany.
Stefan PelzerEvonik Operations GmbH, 63457 Hanau-Wolfgang, Germany.
Monika FlügelEvonik Operations GmbH, 63457 Hanau-Wolfgang, Germany.
Bodo SpeckmannEvonik Operations GmbH, 63457 Hanau-Wolfgang, Germany.
Ruggiero FrancavillaInterdisciplinary Department of Medicine-Pediatric Section, University of Bari Aldo Moro, Ospedale Pediatrico Giovanni XXIII, 70125 Bari, Italy.ORCID 0000-0002-4603-974X
Marco GobbettiFaculty of Science and Technology, Free University of Bozen, 39100 Bolzano, Italy.
Evonik (Germany) · DEUniversity of Bari Aldo Moro · ITFree University of Bozen-Bolzano · ITOspedale Pediatrico Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to define the microbial consortia that are able to digest gluten into non-toxic and non-immunogenic peptides in the human gastrointestinal tract.

methods131 out of 504 tested

resultstwo microbial consortia (Consortium 4:

conclusionsthe results of this study provide evidence that selected microbial consortia could potentially improve the digestion of gluten in gluten-sensitive patients by hydrolyzing the immunogenic peptides during gastrointestinal digestion.

Indexed as

DigestionBacillusBacteriaDuodenumEpitopesGastrointestinal MicrobiomeGastrointestinal TractGlutensHumansHydrolysisMicrobial ConsortiaPeptide HydrolasesPeptidesEpitopesGlutensPeptide HydrolasesPeptidesBacillusbacterial peptidasesgluten epitopesLacticaseibacillusLactiplantibacillusLimosilactobacillus

Identifiers

PMID33808622
PMCPMC8003469
OpenAlexW3136791420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.