ArticleCancers2021
Relative Sensitivity of Core-Needle Biopsy and Incisional Biopsy in the Diagnosis of Musculoskeletal Sarcomas.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Conclusiveness of biopsy techniques for diagnosis of bone and soft tissue tumours: a retrospective, single-centre observational study.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Observational
- Histopathological features of chest wall masses: a systematic review.Annals of medicine and surgery (2012) · 2025Article
- What Is the Prevalence and Fate of Myxoid Soft-Tissue Tumors With an Indeterminate Diagnosis Prior to Resection?Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Distinguishing benign and malignant myxoid soft tissue tumors: Performance of radiomics vs. radiologists.PloS one · 2025Article
- First Experiences with Fusion of PET-CT and MRI Datasets for Navigation-Assisted Percutaneous Biopsies for Primary and Metastatic Bone Tumors.Diagnostics (Basel, Switzerland) · 2024Article
- Mediastinal Epithelioid Angiosarcoma, New Insights into an Uncommon Diagnosis: A Case Report and Literature Review.Hawai'i journal of health & social welfare · 2023Review
- The diagnostic accuracy of 332 incisional biopsies in patients with malignant tumors in the musculoskeletal system.World journal of surgical oncology · 2023Article
- Dedifferentiation in low-grade osteosarcoma: a Japanese Musculoskeletal Oncology Group (JMOG) study.International journal of clinical oncology · 2022Article
- Fifty years of bone tumors.Journal of surgical oncology · 2022Article
- Can homogeneous, lipomatous tumors be primarily resected without biopsy? A retrospective analysis of 240 tumors.World journal of surgical oncology · 2022Article
- Article
- Sarcomas of the extremities and the pelvis: comparing local recurrence after incisional and after core-needle biopsy.World journal of surgical oncology · 2022Article
- Article
- Percutaneous Core Needle Biopsy Can Efficiently and Safely Diagnose Most Primary Bone Tumors.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is no evidence as to the diagnostic value of the two most frequently used methods of biopsies in sarcomas: Incisional or core needle biopsy. The aim of our study was to evaluate the diagnostic sensitivity of the incisional and the core needle biopsy techniques in the diagnosis of bone and soft tissue sarcomas.
methodsWe included 417 patients with a definitive diagnosis of bone or soft tissue sarcoma in whom a total of 472 biopsies had been performed. We correlated the results of the biopsies with the result of the definitive histopathological examination of the resected tumor. Dignity, entity, and grading (whenever possible) of the tissue samples were evaluated.
resultsA total of 258 biopsies (55%) were performed in order to diagnose a soft tissue tumor and 351 biopsies (74.4%) were core needle biopsies. The number of repeat core needle biopsies, necessitated because of inconclusive histopathological results, was significantly higher (50 vs. 5;
conclusionsThis study represents the largest study on biopsies for bone and soft tissue sarcomas. Based only on our results, we are unable to favor one method of biopsy and found high accuracy with both methods. Considering the potential complications, the added oncological risks of incisional biopsies and the ready availability of core needle biopsies, the latter, in our assessment, represents a valid and favourable method for bone and soft tissue sarcomas.
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