Evidence map›Paper›PMID 33808583›Full record

ArticlePathogens (Basel, Switzerland)2021

Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine.

Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Mohamed El Sayes, Ahmed N El Taweel, Maha AlKhazindar, Elsayed T AbdElSalam, Rabeh El-Shesheny, Ghazi Kayali and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yassmin MoatasimCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.
Ahmed KandeilCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.ORCID 0000-0003-3253-6961
Ahmed MostafaCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.ORCID 0000-0002-2878-5714
Omnia KutkatCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.
Mohamed El SayesCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.
Ahmed N El TaweelCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.
Maha AlKhazindarDepartment of Botany and Microbiology, Faculty of Science, Cairo University, Gamaa Street, Giza 12613, Egypt.ORCID 0000-0002-3244-9377
Elsayed T AbdElSalamDepartment of Botany and Microbiology, Faculty of Science, Cairo University, Gamaa Street, Giza 12613, Egypt.
Rabeh El-SheshenyCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.ORCID 0000-0002-8798-2240
Ghazi KayaliHuman Link, Dubai, United Arab Emirates.
Mohamed A AliCenter of Scientific Excellence for Influenza Virus, National Research Centre, Environmental Research Division, Giza 12622, Egypt.ORCID 0000-0002-5615-3212
National Research Centre · EGCairo University · EGSt. Jude Children's Research Hospital · USThe University of Texas Health Science Center at Houston · US

Funding

NIAID NIH HHS HHSN272201400006CScience and Technology Development Fund 5175
6 · The paper itself

Abstract

Since its emergence in 2014, the highly pathogenic avian influenza H5N8 virus has continuously and rapidly spread worldwide in the poultry sector resulting in huge economic losses. A typical inactivated H5N8 vaccine is prepared using the six internal genes from A/PR8/1934 (H1N1) and the two major antigenic proteins (HA and NA) from the circulating H5N8 strain with the HA modified to a low pathogenic form (PR8

Indexed as

H5N8humoral immunityinnate immunityPR8-based influenza vaccinevaccine efficacy

Identifiers

PMID33808583
PMCPMC8003407
OpenAlexW3137545769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.