Evidence map›Paper›PMID 33808512›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Current Treatment Approaches and Outcomes in the Management of Rectal Cancer Above the Age of 80.

Ali P Mourad, Marie Shella De Robles, Soni Putnis, Robert D R Winn

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali P MouradDepartment of Surgery, The Wollongong Hospital, Wollongong, NSW 2500, Australia.ORCID 0000-0003-1093-4352
Marie Shella De RoblesDepartment of Surgery, The Wollongong Hospital, Wollongong, NSW 2500, Australia.ORCID 0000-0001-5753-8344
Soni PutnisDepartment of Surgery, The Wollongong Hospital, Wollongong, NSW 2500, Australia.
Robert D R WinnDepartment of Surgery, The Wollongong Hospital, Wollongong, NSW 2500, Australia.ORCID 0000-0003-4251-9815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of cases of rectal cancer in our older cohort is expected to rise with our ageing population. In this study, we analysed patterns in treatment and the long-term outcomes of patients older than 80 years with rectal cancer across a health district.

methodsAll cases of rectal cancer managed at the Illawarra Cancer Care Centre, Australia between 2006 and 2018 were analysed from a prospectively maintained database. Patients were stratified into three age groups: ≤65 years, 66-79 years and ≥80 years of age. The clinicopathological characteristics, operative and non-operative treatment approach and survival outcomes of the three groups were compared.

resultsSix hundred and ninety-nine patients with rectal cancer were managed, of which 118 (17%) were aged 80 and above. Patients above 80 were less likely to undergo surgery (71% vs. 90%,

conclusionPatients above the age of 80 with rectal cancer exhibit poorer cancer-specific survival, which is accounted for in the first year after diagnosis. Priority should be made to optimise care during this period. There is a need for further research to establish the role of chemoradiotherapy in this population, which appears to be underutilised.

Indexed as

Rectal NeoplasmsAgedChemoradiotherapy, AdjuvantHumansKaplan-Meier EstimateNeoadjuvant TherapyTreatment Outcomeagedchemotherapyradiotherapyrectal neoplasmssurgerysurvival

Identifiers

PMID33808512
PMCPMC8078162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.