Evidence map›Paper›PMID 33808409›Full record

ArticleJournal of clinical medicine2021

High Plasma Cystine Levels Are Associated with Blood Pressure and Reversed by CPAP in Patients with Obstructive Sleep Apnea.

Raphael Boneberg, Anita Pardun, Lena Hannemann, Olaf Hildebrandt, Ulrich Koehler, Ralf Kinscherf, Wulf Hildebrandt

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  12. Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications.Computational and mathematical methods in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raphael BonebergDepartment of Medical Cell Biology, Institute for Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35032 Marburg, Germany.
Anita PardunDepartment of Medical Cell Biology, Institute for Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35032 Marburg, Germany.
Lena HannemannDepartment of Medical Cell Biology, Institute for Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35032 Marburg, Germany.
Olaf HildebrandtDepartment of Sleep Medicine, Division of Pneumology, Internal Medicine, University Clinics of Marburg, UKGM, Baldingerstr. 43, 35043 Marburg, Germany.
Ulrich KoehlerDepartment of Sleep Medicine, Division of Pneumology, Internal Medicine, University Clinics of Marburg, UKGM, Baldingerstr. 43, 35043 Marburg, Germany.
Ralf KinscherfDepartment of Medical Cell Biology, Institute for Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35032 Marburg, Germany.
Wulf HildebrandtDepartment of Medical Cell Biology, Institute for Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35032 Marburg, Germany.
Philipps University of Marburg · DE

Funding

Von-Behring-Röntgen-Stiftung 580071
6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) independent of obesity (OBS) imposes severe cardiovascular risk. To what extent plasma cystine concentration (CySS), a novel pro-oxidative vascular risk factor, is increased in OSA with or without OBS is presently unknown. We therefore studied CySS together with the redox state and precursor amino acids of glutathione (GSH) in peripheral blood mononuclear cells (PBMC) in untreated male patients with OSA (apnea-hypopnea-index (AHI) > 15 h

Indexed as

breathing-disordercardiovascular riskglutathioneintermittent hypoxiaoxidative stresssleep

Identifiers

PMID33808409
PMCPMC8037115
OpenAlexW3152458955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.