ReviewNutrients2021
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 225 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
225 citing papers in PubMed, 6 syntheses or guidelines pooled it, 486 citations in OpenAlex.
- The role of magnesium hydrogels in bone regeneration: a systematic review and meta-analysis.Journal of materials science. Materials in medicine · 2025Pooled it
- The effect of magnesium supplementation on serum concentration of lipid profile: an updated systematic review and dose-response meta-analysis on randomized controlled trials.Nutrition journal · 2025Pooled it
- A systematic review and meta-analysis of the relationship between magnesium levels and malaria severity.Scientific reports · 2024Pooled it
- Magnesium Alloys in Orthopedics: A Systematic Review on Approaches, Coatings and Strategies to Improve Biocompatibility, Osteogenic Properties and Osteointegration Capabilities.International journal of molecular sciences · 2023Pooled it
- Circulating magnesium as a potential risk stratification tool for sudden cardiac death: a systematic review.Herzschrittmachertherapie & Elektrophysiologie · 2023Pooled it
- Physiological Benefits and Performance of Sea Water Ingestion for Athletes in Endurance Events: A Systematic Review.Nutrients · 2022Pooled it
- Randomized, open-label study of the short-term pharmacokinetics of oral magnesium oxide in healthy volunteers.Scientific reports · 2026Trial
- Effects of magnesium concentration on the regulation of nutrition and inflammation in nutritional support for cancer patients.The oncologist · 2025Trial
- The effects of magnesium L-threonate (MagteinFrontiers in nutrition · 2025Trial
- Evaluation of Aluminum and Magnesium Absorption Following the Oral Administration of an Antacid Suspension Containing Magaldrate in Healthy Women Under Fed Conditions.Advances in therapy · 2024Trial
- Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.Frontiers in endocrinology · 2024Trial
- Restoring cartilage-subchondral bone metabolism with biphasic magnesium microspheres ameliorate early osteoarthritis.Bioactive materials · 2026Article
- Effect of the Δ12-acyl-lipid desaturase gene insert and expression under the control of the CBF1 promoter on resistance tobacco to the cold stress.Protoplasma · 2026Article
- Serum magnesium and depressive symptoms among U.S. adults: A cross-sectional study of NHANES august 2021-august 2023.Medicine · 2026Article
- Comparative Analysis of Selected Biochemical Markers Involved in Antioxidative, Immune Responses, and Thyroid Function in Wistar Rats Fed Diets Containing Baked Sprats.Molecules (Basel, Switzerland) · 2026Article
- Letter to the Editor: Magnesium supplementation in sepsis: A promising metabolic resuscitation strategy.World journal of critical care medicine · 2026Article
- Point-of-care magnesium monitoring in athletes: a physiological framework for exercise-related arrhythmic vulnerability.European journal of applied physiology · 2026Review
- Magnesium and nerve injury: Mechanisms and applications.Neural regeneration research · 2026Article
- Maternal potassium-magnesium sulfate supplementation in low-protein diets improves performance and health of sows and suckling piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Magnesium and Diabetes: A Review of Recent Studies on the Efficacy of Supplementation with Mg in Humans Suffering from This Chronic Metabolic Disease.International journal of molecular sciences · 2026Review
165 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnesium plays an important role in many physiological functions. Habitually low intakes of magnesium and in general the deficiency of this micronutrient induce changes in biochemical pathways that can increase the risk of illness and, in particular, chronic degenerative diseases. The assessment of magnesium status is consequently of great importance, however, its evaluation is difficult. The measurement of serum magnesium concentration is the most commonly used and readily available method for assessing magnesium status, even if serum levels have no reliable correlation with total body magnesium levels or concentrations in specific tissues. Therefore, this review offers an overview of recent insights into magnesium from multiple perspectives. Starting from a biochemical point of view, it aims at highlighting the risk due to insufficient uptake (frequently due to the low content of magnesium in the modern western diet), at suggesting strategies to reach the recommended dietary reference values, and at focusing on the importance of detecting physiological or pathological levels of magnesium in various body districts, in order to counteract the social impact of diseases linked to magnesium deficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.