Evidence map›Paper›PMID 33808240›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Improved Semantic Segmentation of Tuberculosis-Consistent Findings in Chest X-rays Using Augmented Training of Modality-Specific U-Net Models with Weak Localizations.

Sivaramakrishnan Rajaraman, Les R Folio, Jane Dimperio, Philip O Alderson, Sameer K Antani

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Assessing Inter-Annotator Agreement for Medical Image Segmentation.IEEE access : practical innovations, open solutions · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sivaramakrishnan RajaramanNational Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.ORCID 0000-0003-0871-8634
Les R FolioRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD 20894, USA.
Jane DimperioRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD 20894, USA.
Philip O AldersonSchool of Medicine, Saint Louis University, St. Louis, MO 63104, USA.
Sameer K AntaniNational Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.ORCID 0000-0002-0040-1387

Funding

Machine learning and artificial intelligence research for clinical medical image processingZIALM010018 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ANTANI, SAMEER · 2021 to 2025
$9.0M
6 · The paper itself

Abstract

Deep learning (DL) has drawn tremendous attention for object localization and recognition in both natural and medical images. U-Net segmentation models have demonstrated superior performance compared to conventional hand-crafted feature-based methods. Medical image modality-specific DL models are better at transferring domain knowledge to a relevant target task than those pretrained on stock photography images. This character helps improve model adaptation, generalization, and class-specific region of interest (ROI) localization. In this study, we train chest X-ray (CXR) modality-specific U-Nets and other state-of-the-art U-Net models for semantic segmentation of tuberculosis (TB)-consistent findings. Automated segmentation of such manifestations could help radiologists reduce errors and supplement decision-making while improving patient care and productivity. Our approach uses the publicly available TBX11K CXR dataset with weak TB annotations, typically provided as bounding boxes, to train a set of U-Net models. Next, we improve the results by augmenting the training data with weak localization, postprocessed into an ROI mask, from a DL classifier trained to classify CXRs as showing normal lungs or suspected TB manifestations. Test data are individually derived from the TBX11K CXR training distribution and other cross-institutional collections, including the Shenzhen TB and Montgomery TB CXR datasets. We observe that our augmented training strategy helped the CXR modality-specific U-Net models achieve superior performance with test data derived from the TBX11K CXR training distribution and cross-institutional collections (

Indexed as

augmentationchest-X-raysconvolutional neural networksdeep learninglocalizationmodality-specific knowledge transfersegmentationtuberculosisU-Net

Identifiers

PMID33808240
PMCPMC8065621

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.