Evidence map›Paper›PMID 33808208›Full record

ReviewBiomolecules2021

The 40-Year Mystery of Insect Odorant-Binding Proteins.

Karen Rihani, Jean-François Ferveur, Loïc Briand

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 205 citations in OpenAlex.

  1. Article
  2. Rapidly evolving aphid gall effector proteins exhibit saposin-like folds.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  11. Neuroproteomic Profiling of the Anxiolytic Potential ofInternational journal of molecular sciences · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Beyond olfaction: New insights into human odorant binding proteins.Protein science : a publication of the Protein Society · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karen RihaniDijon, CNRS, INRAE, Université de Bourgogne Franche-Comté, Centre des Sciences du Goût et de l'Alimentation, 21000 Dijon, France.ORCID 0000-0001-7407-9311
Jean-François FerveurDijon, CNRS, INRAE, Université de Bourgogne Franche-Comté, Centre des Sciences du Goût et de l'Alimentation, 21000 Dijon, France.ORCID 0000-0002-4022-686X
Loïc BriandDijon, CNRS, INRAE, Université de Bourgogne Franche-Comté, Centre des Sciences du Goût et de l'Alimentation, 21000 Dijon, France.
Centre National de la Recherche Scientifique · FR

Funding

Conseil régional de Bourgogne-Franche-Comté (PARI grant)European Funding for Regional Economic Development FEDER
6 · The paper itself

Abstract

The survival of insects depends on their ability to detect molecules present in their environment. Odorant-binding proteins (OBPs) form a family of proteins involved in chemoreception. While OBPs were initially found in olfactory appendages, recently these proteins were discovered in other chemosensory and non-chemosensory organs. OBPs can bind, solubilize and transport hydrophobic stimuli to chemoreceptors across the aqueous sensilla lymph. In addition to this broadly accepted "transporter role", OBPs can also buffer sudden changes in odorant levels and are involved in hygro-reception. The physiological roles of OBPs expressed in other body tissues, such as mouthparts, pheromone glands, reproductive organs, digestive tract and venom glands, remain to be investigated. This review provides an updated panorama on the varied structural aspects, binding properties, tissue expression and functional roles of insect OBPs.

Indexed as

AnimalsEvolution, MolecularGene ExpressionHematopoiesisInsectaInsect ProteinsPheromonesReceptors, OdorantSexual Behavior, AnimalInsect Proteinsodorant-binding proteinPheromonesReceptors, Odorantchemosensory functionsDrosophila melanogasterinsectnon-chemosensory functionsodorant-protein-binding assayolfactiontaste

Identifiers

PMID33808208
PMCPMC8067015
OpenAlexW3152352793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.