Evidence map›Paper›PMID 33808169›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Novel Blood Biomarkers for a Diagnostic Workup of Acute Aortic Dissection.

Anja Forrer, Felix Schoenrath, Michael Torzewski, Jens Schmid, Urlich F W Franke, Nora Göbel, Drahomir Aujesky, Christian M Matter, Thomas F Lüscher, Francois Mach and 5 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  12. The diagnostic value of tenascin-C in acute aortic syndrome.Journal of geriatric cardiology : JGC · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Anja ForrerInstitute of Clinical Chemistry, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-2839-0149
Felix SchoenrathDepartment of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, 13353 Berlin, Germany.
Michael TorzewskiDepartment of Laboratory Medicine and Hospital Hygiene, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Jens SchmidDepartment of Laboratory Medicine and Hospital Hygiene, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Urlich F W FrankeDepartment of Cardiovascular Surgery, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Nora GöbelDepartment of Cardiovascular Surgery, Robert Bosch Hospital, 70376 Stuttgart, Germany.ORCID 0000-0002-7692-3480
Drahomir AujeskyDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Christian M MatterDepartment of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Thomas F LüscherDepartment of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Francois MachDepartment of Cardiology, University Hospital Geneva, 1205 Geneva, Switzerland.
David NanchenCenter for Primary Care and Public Health, University of Lausanne, 1015 Lausanne, Switzerland.
Nicolas RodondiDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Volkmar FalkDepartment of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, 13353 Berlin, Germany.
Arnold von EckardsteinInstitute of Clinical Chemistry, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-1666-2266
Joanna GawineckaInstitute of Clinical Chemistry, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.
University of Zurich · CHRobert Bosch Hospital · DEUniversity of Bern · CHDeutsches Herzzentrum der Charité · DEETH Zurich · CHUniversity Hospital of Geneva · CHUniversity of Lausanne · CH

Funding

HMZ Seed Project, University Hospital ZurichRobert Bosch-FoundationStiftung für Pathobiochemie und Molekulare DiagnostikUniversity Hospital Zurich Foundation
6 · The paper itself

Abstract

Acute aortic dissection (AAD) is a rare condition, but together with acute myocardial infarction (AMI) and pulmonary embolism (PE) it belongs to the most relevant and life-threatening causes of acute chest pain. Until now, there has been no specific blood test in the diagnostic workup of AAD. To identify clinically relevant biomarkers for AAD, we applied Proseek

Indexed as

acute aortic dissectionacute myocardial infarctionbiomarkerD-dimersIL-10pulmonary embolism

Identifiers

PMID33808169
PMCPMC8065878
OpenAlexW3139558414

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.