Evidence map›Paper›PMID 33808091›Full record

ArticleJournal of personalized medicine2021

Modulation of the Dental Pulp Stem Cell Secretory Profile by Hypoxia Induction Using Cobalt Chloride.

Shilpa Bhandi, Ahmed Al Kahtani, Mohammed Mashyakhy, Loai Alsofi, Prabhadevi C Maganur, Satish Vishwanathaiah, Luca Testarelli, Andrea Del Giudice, Deepak Mehta, Nishant Vyas and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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  10. Metformin pre-conditioning enhances the angiogenic ability of the secretome of dental pulp stem cells.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Shilpa BhandiDepartment of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.
Ahmed Al KahtaniDepartment of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammed MashyakhyDepartment of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.
Loai AlsofiDepartment of Endodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-0430-0268
Prabhadevi C MaganurDepartment of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-0959-2597
Satish VishwanathaiahDepartment of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-8376-297X
Luca TestarelliDepartment of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3904-3000
Andrea Del GiudiceDepartment of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.
Deepak MehtaDepartment of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.
Nishant VyasLogical Life Science Private Limited, Pune 411041, India.
Vikrant R PatilLogical Life Science Private Limited, Pune 411041, India.ORCID 0000-0003-0017-5807
A Thirumal RajDepartment of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai 600130, India.ORCID 0000-0002-1079-1024
Shankargouda PatilDepartment of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-7246-5497
Jazan University · SASapienza University of Rome · ITKing Abdulaziz University · SAKing Saud University · SASri Venkateswara Medical College and Ruia Hospital · INUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The action of stem cells is mediated by their paracrine secretions which comprise the secretory profile. Various approaches can be used to modify the secretory profile of stem cells. Creating a hypoxic environment is one method. The present study aims to demonstrate the influence of CoCl

Indexed as

cobalt chloridedental pulp stem cellshypoxia inducible factorsecretory profilestemness

Identifiers

PMID33808091
PMCPMC8066657
OpenAlexW3150878795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.