Evidence map›Paper›PMID 33808054›Full record

ArticleMolecules (Basel, Switzerland)2021

The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure-Activity Relationship.

Thi Thanh Hanh Nguyen, Jong-Hyun Jung, Min-Kyu Kim, Sangyong Lim, Jae-Myoung Choi, Byoungsang Chung, Do-Won Kim, Doman Kim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Current issues in molecular biology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Investigation of phytochemicals isolated from selected Saudi medicinal plants as natural inhibitors of SARS CoV-2 main protease: In vitroSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  9. Article
  10. Review
  11. Antiviral Effects of Secondary Metabolites fromPlants (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Thi Thanh Hanh NguyenInstitutes of Green Bioscience and Technology, Seoul National University, Pyeongchang-gun 25354, Gang-won-do, Korea.
Jong-Hyun JungRadiation Research Division, Korea Atomic Engery Research Institute, Jeongeup 56212, Jeollabuk-do, Korea.
Min-Kyu KimRadiation Research Division, Korea Atomic Engery Research Institute, Jeongeup 56212, Jeollabuk-do, Korea.ORCID 0000-0001-9594-1396
Sangyong LimRadiation Research Division, Korea Atomic Engery Research Institute, Jeongeup 56212, Jeollabuk-do, Korea.ORCID 0000-0002-0359-5180
Jae-Myoung ChoiOttogi Sesame Mills Co., Ltd., Eumseong-gun 27623, Chungcheongbuk-do, Korea.
Byoungsang ChungOttogi Sesame Mills Co., Ltd., Eumseong-gun 27623, Chungcheongbuk-do, Korea.
Do-Won KimDepartment of Physics, Gangneung-Wonju National University, Gangneung 25457, Gangwon-do, Korea.
Doman KimInstitutes of Green Bioscience and Technology, Seoul National University, Pyeongchang-gun 25354, Gang-won-do, Korea.ORCID 0000-0003-0389-3441
Gangneung–Wonju National University · KRKorea Atomic Energy Research Institute · KRSeoul National University · KR

Funding

National Research Foundation of Korea 2018R1D1A1B07049569, 2018R1D1A1A09083366, NRF-2018R1C1B6006348Nuclear R&D program of Ministry of Science and ICTOttogi Sesame Mills Co
6 · The paper itself

Abstract

The main protease (M

Indexed as

Coronavirus 3C ProteasesDimethyl SulfoxideDrug SynergismGarlicHydrogen-Ion ConcentrationPlant ExtractsPlantsPolyphenolsProtease InhibitorsStructure-Activity RelationshipTemperatureCoronavirus 3C ProteasesDimethyl SulfoxidePlant ExtractsPolyphenolsProtease Inhibitorsblack garlickineticmain proteasepolyphenolSARS-CoV-2structure–activity relationship

Identifiers

PMID33808054
PMCPMC8036510
OpenAlexW3140346797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.