Evidence map›Paper›PMID 33807825›Full record

ArticlePolymers2021

Assessing the Influence of Dyes Physico-Chemical Properties on Incorporation and Release Kinetics in Silk Fibroin Matrices.

Bruno Thorihara Tomoda, Murilo Santos Pacheco, Yasmin Broso Abranches, Juliane Viganó, Fabiana Perrechil, Mariana Agostini De Moraes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bruno Thorihara TomodaDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.ORCID 0000-0003-2609-5493
Murilo Santos PachecoDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.
Yasmin Broso AbranchesDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.
Juliane ViganóDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.
Fabiana PerrechilDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.ORCID 0000-0001-7543-3837
Mariana Agostini De MoraesDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil.ORCID 0000-0002-2586-6834
Universidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/15539-6
6 · The paper itself

Abstract

Silk fibroin (SF) is a promising and versatile biodegradable protein for biomedical applications. This study aimed to develop a prolonged release device by incorporating SF microparticles containing dyes into SF hydrogels. The influence of dyes on incorporation and release kinetics in SF based devices were evaluated regarding their hydrophilicity, molar mass, and cationic/anionic character. Hydrophobic and cationic dyes presented high encapsulation efficiency, probably related to electrostatic and hydrophobic interactions with SF. The addition of SF microparticles in SF hydrogels was an effective method to prolong the release, increasing the release time by 10-fold.

Indexed as

biopolymerdye releasehydrogelmicroparticles

Identifiers

PMID33807825
PMCPMC7961930
OpenAlexW3133489612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.