Evidence map›Paper›PMID 33807793›Full record

ArticleHealthcare (Basel, Switzerland)2021

Primary Extra-Nodal DLBCL of Glands: Our Experiences outside Guidelines of Treatment.

Antonello Sica, Mario Santagata, Caterina Sagnelli, Piero Rambaldi, Renato Franco, Massimiliano Creta, Paola Vitiello, Stefano Caccavale, Vincenzo Tammaro, Evangelista Sagnelli and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Antonello SicaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-8676-4620
Mario SantagataMultidisciplinary Department of Medical Surgery and Dental Specialties, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Caterina SagnelliDepartment of Mental Health and Public Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-6413-7810
Piero RambaldiDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Renato FrancoDivision of Pathology, Department of Mental Health and Preventive, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Massimiliano CretaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Paola VitielloDermatology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Stefano CaccavaleDermatology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Vincenzo TammaroDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Evangelista SagnelliDepartment of Mental Health and Public Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Andrea RonchiDivision of Pathology, Department of Mental Health and Preventive, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphomas usually involve lymph nodes and other lymphoid tissues, but sometimes occur in non-lymphoid organs, called extra-nodal sites. Primary diffuse extra-lymph node large B-cell lymphoma (DLBCL) of the thyroid and parotid gland have been observed rarely. According to the most accredited guidelines, primary extra-nodal DLBCL of the parotid and thyroid glands should be treated with three cycles of R-CHOP followed by radiotherapy of the involved site (ISRT). Surgery alone is not enough to treat DLBCL. We describe two unusual cases of primary extra-nodal DLBCL in elderly patients treated exclusively with surgical resection, given the inability to apply chemotherapy. Both patients achieved clinical recovery, which was maintained after a follow-up of more than 18 months, despite not having performed the indicated chemotherapy protocol. The two cases presented here, and a few others reported in the literature, should be considered exceptions to the rule, and do not allow the conclusion that surgery alone might be sufficient for complete remission.

Indexed as

non-Hodgkin lymphomaparotid gland lymphomaprimary extra-nodal lymphomathyroid lymphoma

Identifiers

PMID33807793
PMCPMC8002204
OpenAlexW3135834389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.