Evidence map›Paper›PMID 33807635›Full record

ArticleInternational journal of molecular sciences2021

Shorter P1m Response in Children with Autism Spectrum Disorder without Intellectual Disabilities.

Yuko Yoshimura, Takashi Ikeda, Chiaki Hasegawa, Kyung-Min An, Sanae Tanaka, Ken Yaoi, Sumie Iwasaki, Daisuke N Saito, Hirokazu Kumazaki, Hirotoshi Hiraishi and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yuko YoshimuraInstitute of Human and Social Sciences, Kanazawa University, Kanazawa 920-1192, Japan.
Takashi IkedaResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Chiaki HasegawaResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Kyung-Min AnResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Sanae TanakaResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Ken YaoiResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Sumie IwasakiResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Daisuke N SaitoFaculty of Psychology, Yasuda Women's University, Hiroshima 731-0153, Japan.
Hirokazu KumazakiDepartment of Preventive Intervention for Psychiatric Disorders, National Center of Neurology and Psychiatry, Tokyo 187-8553, Japan.
Hirotoshi HiraishiDepartment of Biofunctional Imaging, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Mitsuru KikuchiResearch Center for Child Mental Development, Kanazawa University, Kanazawa 920-8640, Japan.
Kanazawa University · JPHamamatsu University School of Medicine · JPNational Center of Neurology and Psychiatry · JPYasuda Women's University · JP

Funding

Japan Science and Technology Agency the Center of Innovation ProgramJapan Society for the Promotion of Science 19K02952Japan Society for the Promotion of Science 20H04993
6 · The paper itself

Abstract

(1) Background: Atypical auditory perception has been reported in individuals with autism spectrum disorder (ASD). Altered auditory evoked brain responses are also associated with childhood ASD. They are likely to be associated with atypical brain maturation. (2) Methods: This study examined children aged 5-8 years old: 29 with ASD but no intellectual disability and 46 age-matched typically developed (TD) control participants. Using magnetoencephalography (MEG) data obtained while participants listened passively to sinusoidal pure tones, bilateral auditory cortical response (P1m) was examined. (3) Results: Significantly shorter P1m latency in the left hemisphere was found for children with ASD without intellectual disabilities than for children with TD. Significant correlation between P1m latency and language conceptual ability was found in children with ASD, but not in children with TD. (4) Conclusions: These findings demonstrated atypical brain maturation in the auditory processing area in children with ASD without intellectual disability. Findings also suggest that ASD has a common neural basis for pure-tone sound processing and language development. Development of brain networks involved in language concepts in early childhood ASD might differ from that in children with TD.

Indexed as

Auditory CortexAutism Spectrum DisorderChildChild, PreschoolEvoked Potentials, AuditoryFemaleHumansIntellectual DisabilityMagnetoencephalographyMaleReaction Timeauditory cortexautism spectrum disordermagnetoencephalographyP1m response

Identifiers

PMID33807635
PMCPMC7961676
OpenAlexW3133726277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.