Evidence map›Paper›PMID 33807627›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Rare Causes of Arterial Hypertension and Thoracic Aortic Aneurysms-A Case-Based Review.

Svetlana Encica, Adrian Molnar, Simona Manole, Teodora Filan, Simona Oprița, Eugen Bursașiu, Romana Vulturar, Laura Damian

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Journal of vascular surgery cases and innovative techniques · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Svetlana EncicaDepartment of Pathology, "Niculae Stancioiu" Heart Institute Cluj-Napoca, 19-21, Calea Moților St, 400001 Cluj-Napoca, Romania.
Adrian MolnarDepartment of Cardiovascular Surgery, "Niculae Stancioiu" Heart Institute Cluj Napoca, 19-21, Calea Moților St, 400001 Cluj-Napoca, Romania.
Simona ManoleDepartment of Radiology, "Niculae Stancioiu" Heart Institute 19-21, Calea Moților St, 400001 Cluj-Napoca, Romania.
Teodora FilanDepartment of Cardiology, Emergency County Hospital Alba, 23, Revoluției 1989, 510077 Alba-Iulia, Romania.
Simona OprițaDepartment of Cardiovascular Surgery, "Niculae Stancioiu" Heart Institute Cluj Napoca, 19-21, Calea Moților St, 400001 Cluj-Napoca, Romania.
Eugen BursașiuDepartment of Radiology, "Niculae Stancioiu" Heart Institute 19-21, Calea Moților St, 400001 Cluj-Napoca, Romania.
Romana VulturarDepartment of Molecular Sciences, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca Romania, 6, Pasteur, 400349 Cluj-Napoca, Romania.ORCID 0000-0003-2476-9706
Laura DamianCMI Reumatologie Dr. Damian, 6-8 Petru Maior St, 400002 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thoracic aortic aneurysms may result in dissection with fatal consequences if undetected. A young male patient with no relevant familial history, after having been investigated for hypertension, was diagnosed with an ascending aortic aneurysm involving the aortic root and the proximal tubular segment, associated with a septal atrial defect. The patient underwent a Bentall surgery protocol without complications. Clinical examination revealed dorso-lumbar scoliosis and no other signs of underlying connective tissue disease. Microscopic examination revealed strikingly severe medial degeneration of the aorta, with areas of deep disorganization of the medial musculo-elastic structural units and mucoid material deposition. Genetic testing found a variant of unknown significance the

Indexed as

hypertensionPKG-1β isoformPRKG1 mutationscoliosissmooth muscle cellsthoracic aortic aneurysm

Identifiers

PMID33807627
PMCPMC8001303
OpenAlexW3135840565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.