Evidence map›Paper›PMID 33807557›Full record

ArticleViruses2021

Non-Polio Enteroviruses from Acute Flaccid Paralysis Surveillance in Korea, 2012-2019.

Youngsil Yoon, Yong-Pyo Lee, Deog-Yong Lee, Hye-Jin Kim, June-Woo Lee, Sangwon Lee, Chun Kang, Wooyoung Choi, Joong Hyun Bin, Young Hoon Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Youngsil YoonDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Yong-Pyo LeeDivision of Infectious Disease Diagnosis Control, Regional Centers for Disease Control and Prevention, Korea~Disease Control and Prevention Agency, Cheongju 28159, Korea.
Deog-Yong LeeDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Hye-Jin KimDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
June-Woo LeeDivision of Vaccine Clinical Research, National Institute of Health, Cheongju 28159, Korea.
Sangwon LeeDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Chun KangDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Wooyoung ChoiDivision of Infectious Disease Diagnosis Control, Regional Centers for Disease Control and Prevention, Korea~Disease Control and Prevention Agency, Cheongju 28159, Korea.
Joong Hyun BinCollege of Medicine, Catholic University of Korea, Seoul 06591, Korea.
Young Hoon KimCollege of Medicine, Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-6151-6911
Myung-Guk HanDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Hae Ji KangDivision of Viral Diseases, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea.
Korea Disease Control and Prevention Agency · KRCatholic University of Korea · KRKorea National Institute of Health · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of polio importation and re-emergence persists since epidemic polio still occurs in some countries, and the resurgence of polio occurring almost 20 years after polio eradication was declared in Asia has been reported. We analyzed the results of acute flaccid paralysis (AFP) surveillance in Korea to assess the quality of AFP surveillance and understand the etiology of non-polio enterovirus (NPEV)-associated central nervous system diseases in a polio-free area. We investigated 637 AFP patients under 15 years of age whose cases were confirmed during 2012-2019 by virus isolation, real-time reverse transcription polymerase chain reaction, and VP1 gene sequencing. Among the 637 AFP cases, NPEV was detected in 213 (33.4%) patients, with the majority observed in EV-A71, with 54.9% of NPEV positives. EV-A71 has been shown to play a role as a major causative agent in most neurological diseases except for Guillain-Barré syndrome (GBS), acute disseminated encephalomyelitis (ADEM), and meningitis. This study provides information on the AFP surveillance situation in Korea and highlights the polio eradication stage in the monitoring and characterization of NPEV against the outbreak of neurological infectious diseases such as polio.

Indexed as

Central Nervous System Viral DiseasesEpidemiological MonitoringMyelitisNeuromuscular DiseasesAdolescentChildChild, PreschoolEnterovirusFemaleHumansInfantMaleRepublic of Koreaacute flaccid paralysis (AFP)enteroviruspoliovirussurveillance

Identifiers

PMID33807557
PMCPMC8001888
OpenAlexW3134310272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.