Evidence map›Paper›PMID 33807513›Full record

ArticleJournal of functional biomaterials2021

Cryo-Structured Materials Based on Polyvinyl Alcohol and Hydroxyapatite for Osteogenesis.

Daria N Lytkina, Dmitriy A Fedorishin, Polina M Kalachikova, Anastasiya A Plyaskina, Aleksandr R Babeshin, Irina A Kurzina

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Daria N LytkinaChemical Department, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.ORCID 0000-0002-7458-6265
Dmitriy A FedorishinChemical Department, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.
Polina M KalachikovaChemical Department, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.
Anastasiya A PlyaskinaChemical Department, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.
Aleksandr R BabeshinDepartment of Surgical Diseases with a Course in Traumatology and Orthopedics, Siberian State Medical University, Moskovsky trakt 2, 634055 Tomsk, Russia.
Irina A KurzinaChemical Department, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.ORCID 0000-0003-4976-2295
National Research Tomsk State University · RUSiberian State Medical University · RUSkolkovo Institute of Science and Technology · RU

Funding

Program of Competitive Recovery of TSU 8.2.10.2018 L
6 · The paper itself

Abstract

The application of various materials in biomedical procedures has recently experienced rapid growth. One of the areas is the treatment of many of different types of bone-related diseases and disorders by using biodegradable polymer-ceramic composites. We have developed a material based on cryogel polyvinyl alcohol, mineralized with calcium phosphate. Composites were obtained by cyclic freezing-thawing, the synthesis of calcium phosphates was carried out in situ under the influence of microwave radiation with heating and stirring. The components of the composites were determined using the methods of IR-spectroscopy and scanning electron microscopy and electron probe microanalyzer, as well as their morphology and surface properties. The biological compatibility of the material was investigated in vivo for a Wistar rat. The assessment of the quality of bone formation between the cryogel-based implant and the damaged bone was carried out by computed tomography. An improvement in the consolidation of the bone defect is observed in the bone with the composite in comparison with the control bone.

Indexed as

biocompatible materialbone repaircalcium phosphatescryogelhydroxyapatitePVA

Identifiers

PMID33807513
PMCPMC8006254
OpenAlexW3133661206

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.