Evidence map›Paper›PMID 33807396›Full record

ArticleViruses2021

High Heterogeneity of Echoviruses in Brazilian Children with Acute Gastroenteritis.

Endrya do Socorro Fôro Ramos, Ulisses Alves Rosa, Geovani de Oliveira Ribeiro, Fabiola Villanova, Flávio Augusto de Pádua Milagres, Rafael Brustulin, Vanessa Dos Santos Morais, Mayara Bertanhe, Roberta Marcatti, Emerson Luiz Lima Araújo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Endrya do Socorro Fôro RamosLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belem 66075-000, Pará, Brazil.
Ulisses Alves RosaLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belem 66075-000, Pará, Brazil.
Geovani de Oliveira RibeiroLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belem 66075-000, Pará, Brazil.ORCID 0000-0002-8832-7803
Fabiola VillanovaLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belem 66075-000, Pará, Brazil.ORCID 0000-0003-4442-5855
Flávio Augusto de Pádua MilagresSecretaria de Saúde do Tocantins, Palmas 77453-000, Tocantins, Brazil.
Rafael BrustulinSecretaria de Saúde do Tocantins, Palmas 77453-000, Tocantins, Brazil.
Vanessa Dos Santos MoraisDepartamento de Moléstias Infecciosas e Parasitárias, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0002-3813-3154
Mayara BertanheDepartamento de Moléstias Infecciosas e Parasitárias, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0002-2240-2874
Roberta MarcattiDepartamento de Moléstias Infecciosas e Parasitárias, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-000, Brazil.
Emerson Luiz Lima AraújoGeneral Coordination of Public Health Laboratories of the Strategic Articulation, Department of the Health Surveillance Secretariat of the Ministry of Health (CGLAB/DAEVS/SVS-MS), Brasília 70719-040, Federal District, Brazil.ORCID 0000-0002-7684-2883
Steven S WitkinDepartamento de Moléstias Infecciosas e Parasitárias, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-000, Brazil.
Eric DelwartVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA 94143, USA.ORCID 0000-0002-6296-4484
Adriana LuchsLaboratório de Doenças Entéricas, Centro de Virologia, Instituto Adolfo Lutz, São Paulo 01246-000, Brazil.
Antonio Charlys da CostaDepartamento de Moléstias Infecciosas e Parasitárias, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0001-5516-5177
Élcio LealLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belem 66075-000, Pará, Brazil.ORCID 0000-0003-3463-0492
Universidade de São Paulo · BRUniversidade Federal do Pará · BRUniversidade do Tocantins · BRInstituto Adolfo Lutz · BRMinistério da Saúde · BRUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echoviruses (E) are a diverse group of viruses responsible for various pathological conditions in humans including aseptic meningitis, myocarditis, and acute flaccid paralysis. The detection and identification of echovirus genotypes in clinical samples is challenging due to its high genetic diversity. Here, we report the complete genome sequences of nine echoviruses, obtained by next-generation sequencing of 238 fecal samples from individuals with gastroenteritis in regions of Brazil. Detected viruses were classified into six genotypes: Three E1 sequences (BRA/TO-028, BRA/TO-069 and BRA/TO-236), one E3 (BRA/TO-018), one E11 (BRA/TO-086), one E20 (BRA/TO-016), two E29 (BRA/TO-030 and BRA/TO-193), and one E30 sequence (BRA/TO-032). Phylogenetic analysis indicated that the echoviruses E1 and E29 circulating in Brazil are divergent from strains circulating worldwide. The genotype diversity identified in our study may under-represent the total echovirus diversity in Brazil because of the small sample size and the restricted geographical distribution covered by the survey.

Indexed as

Genetic VariationGenome, ViralGenotypeAcute DiseaseBrazilChild, PreschoolCross-Sectional StudiesEnterovirus B, HumanEpidemiological MonitoringFecesFemaleGastroenteritisHigh-Throughput Nucleotide SequencingHumansInfantMaleRNA, Viralacute gastroenteritisechovirus Eenterovirusgut viromepediatric virome

Identifiers

PMID33807396
PMCPMC8067319
OpenAlexW3143621754

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.