Evidence map›Paper›PMID 33807338›Full record

ArticleCells2021

Changes in Biomechanical Properties of A375 Cells Due to the Silencing of

Aleksandra Makowiecka, Ewa Mazurkiewicz, Ewa Mrówczyńska, Natalia Malek, Alice Battistella, Marco Lazzarino, Dorota Nowak, Antonina Joanna Mazur

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The Prognostic Significance of TMSB4X in Glioma Patients.International journal of general medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aleksandra MakowieckaDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.ORCID 0000-0001-5030-684X
Ewa MazurkiewiczDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.ORCID 0000-0002-5418-5712
Ewa MrówczyńskaDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.ORCID 0000-0002-1204-6108
Natalia MalekDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.
Alice BattistellaIstituto Officina dei Materiali-National Research Council, I-34149 Trieste, Italy.
Marco LazzarinoIstituto Officina dei Materiali-National Research Council, I-34149 Trieste, Italy.ORCID 0000-0003-1077-6569
Dorota NowakDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.
Antonina Joanna MazurDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wrocław, Poland.
University of Wrocław · PLIstituto Officina dei Materiali · IT

Funding

Foundation for Polish Science START scholarship 050.2017Ministry of Science and Higher Education, Poland 444/STYP/13/2018National Center for Science, Poland ETIUDA 5 2017/24/T/NZ3/00068
6 · The paper itself

Abstract

Thymosin β4 (Tβ4) is a small, 44-amino acid polypeptide. It has been implicated in multiple processes, including cell movement, angiogenesis, and stemness. Previously, we reported that melanoma cell lines differ in Tβ4 levels. Studies on stable clones with silenced

Indexed as

Gene SilencingActin CytoskeletonBiomarkers, TumorBiomechanical PhenomenaCarcinogenesisCell CycleCell Line, TumorCell ProliferationCell ShapeHumansIntermediate FilamentsMelanomaModels, BiologicalNeoplastic Stem CellsNestinThymosinBiomarkers, TumorNestinThymosinThymosin beta(4)Vimentinatomic force microscopy (AFM)clonogenicitycytoskeletonF-actinmelanomamelanoma heterogeneityNestinphenotypic heterogeneitysingle-cell force spectroscopy (SFCS)stemnessstiffnessThymosin β4 (Tβ4)tumorigenicityVimentin

Identifiers

PMID33807338
PMCPMC8067020
OpenAlexW3151040891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.