ReviewCells2021
Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis.
Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 242 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
242 citing papers in PubMed, 2 syntheses or guidelines pooled it, 440 citations in OpenAlex.
- Depression and anxiety in interstitial lung disease: a systematic review, meta-analysis and Mendelian randomization.Translational psychiatry · 2026Pooled it
- Isolated cardiac sarcoidosis: A systematic review.The Journal of international medical research · 2025Pooled it
- Neuro-ophthalmic sarcoidosis with extraocular-muscle involvement: neuroimaging.Arquivos de neuro-psiquiatria · 2026Article
- Hepatic sarcoidosis presenting with portal hypertension without histologically established cirrhosis and reticular hepatic imaging features.Clinical journal of gastroenterology · 2026Article
- Canine Sarcoidosis Treated Successfully With Oclacitinib: A Case Report.Veterinary dermatology · 2026Article
- Unveiling the unexpected: Skeletal sarcoidosis with an extraosseous soft-tissue mass in the ligamentous portion of sacroiliac joint.Radiology case reports · 2026Article
- Tattoo-Associated Systemic Sarcoidosis Treated With JAK Inhibition.International journal of dermatology · 2026Article
- Diagnostic Journey to Granulomatosis with Polyangiitis with Rare Hepatic and Suspected Splenic Involvement: A Case Report.Diseases (Basel, Switzerland) · 2026Article
- Kidney outcomes and prognostic factors in biopsy-proven kidney sarcoidosis: a nationwide multicenter cohort study.Clinical kidney journal · 2026Article
- Miliary lungs in a septuagenarian: Thinking beyond tuberculosis.Lung India : official organ of Indian Chest Society · 2026Article
- Real-world clinical outcomes after cardiac resynchronization therapy in cardiac sarcoidosis.Heart and vessels · 2026Article
- An Endoscopic Ultrasound-guided Fine-needle Biopsy as a Diagnostic Tool for Isolated Hepatic Sarcoidosis.Internal medicine (Tokyo, Japan) · 2026Article
- Article
- Quality of Life in Sarcoidosis.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Auricularia auricula polysaccharides alleviate Propionibacterium acnes-induced lung sarcoidosis-like granulomatosis in mice via the gut-lung axis.Journal of natural medicines · 2026Article
- A Rare Case of Atrophic Sarcoidosis on Upper Limbs Without Skin Ulceration.Indian dermatology online journal · 2026Article
- Organ Involvement and Treatment Response across Cutaneous Sarcoidosis Subtypes.Acta dermato-venereologica · 2026Article
- The Diagnostic Course of Sarcoidosis: A Population-Based Study Highlighting Risk Factors for a Delay in Diagnosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- Sarcoidosis presenting as fulminant bilateral multifocal choroiditis.Journal of ophthalmic inflammation and infection · 2026Article
182 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcoidosis is a multi-system disease of unknown etiology characterized by the formation of granulomas in various organs. It affects people of all ethnic backgrounds and occurs at any time of life but is more frequent in African Americans and Scandinavians and in adults between 30 and 50 years of age. Sarcoidosis can affect any organ with a frequency varying according to ethnicity, sex and age. Intrathoracic involvement occurs in 90% of patients with symmetrical bilateral hilar adenopathy and/or diffuse lung micronodules, mainly along the lymphatic structures which are the most affected system. Among extrapulmonary manifestations, skin lesions, uveitis, liver or splenic involvement, peripheral and abdominal lymphadenopathy and peripheral arthritis are the most frequent with a prevalence of 25-50%. Finally, cardiac and neurological manifestations which can be the initial manifestation of sarcoidosis, as can be bilateral parotitis, nasosinusal or laryngeal signs, hypercalcemia and renal dysfunction, affect less than 10% of patients. The diagnosis is not standardized but is based on three major criteria: a compatible clinical and/or radiological presentation, the histological evidence of non-necrotizing granulomatous inflammation in one or more tissues and the exclusion of alternative causes of granulomatous disease. Certain clinical features are considered to be highly specific of the disease (e.g., Löfgren's syndrome, lupus pernio, Heerfordt's syndrome) and do not require histological confirmation. New diagnostic guidelines were recently published. Specific clinical criteria have been developed for the diagnosis of cardiac, neurological and ocular sarcoidosis. This article focuses on the clinical presentation and the common differentials that need to be considered when appropriate.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.