Evidence map›Paper›PMID 33807288›Full record

ArticleViruses2021

Limited Genetic Diversity Detected in Middle East Respiratory Syndrome-Related Coronavirus Variants Circulating in Dromedary Camels in Jordan.

Stephanie N Seifert, Jonathan E Schulz, Stacy Ricklefs, Michael Letko, Elangeni Yabba, Zaidoun S Hijazeen, Peter Holloway, Bilal Al-Omari, Hani A Talafha, Markos Tibbo and 10 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Stephanie N SeifertVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.ORCID 0000-0002-4397-6156
Jonathan E SchulzVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Stacy RicklefsRocky Mountain Labs Genomics Unit, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Michael LetkoVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Elangeni YabbaVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Zaidoun S HijazeenNational Consultant, Food and Agriculture Organization of the United Nations, Amman 11194, Jordan.
Peter HollowayEconomics and Public Health Group, Royal Veterinary College, Hatfield AL9 7TA, UK.
Bilal Al-OmariDepartment of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Hani A TalafhaDepartment of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Markos TibboSubregional Office for the Gulf Cooperation Council States and Yemen, Food and Agriculture Organization of the United Nations, Abu Dhabi 62072, United Arab Emirates.ORCID 0000-0002-4330-6486
Danielle R AdneyVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Javier GuitianEconomics and Public Health Group, Royal Veterinary College, Hatfield AL9 7TA, UK.
Nadim AmarinTechnical and Marketing Department, United Animal Health, Sheridan, IN 46069, USA.ORCID 0000-0001-6883-4325
Juergen A RichtDepartment of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-7308-5672
Chester McDowellDepartment of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS 66506, USA.
John SteelDepartment of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA.
Ehab A Abu-BashaDepartment of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-2848-9461
Ahmad M Al-MajaliDepartment of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Neeltje van DoremalenVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.ORCID 0000-0003-4368-6359
Vincent J MunsterVirus Ecology Section, Laboratory of Virology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.ORCID 0000-0002-2288-3196
National Institutes of Health · USJordan University of Science and Technology · JOKansas State University · USRoyal Veterinary College · GBCenters for Disease Control and Prevention · USUnited Animal Health (United States) · US

Funding

Virus Ecology UnitZIAAI001179 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MUNSTER, VINCENT · 2013 to 2025
$24.3M
International Research in CongoZIAAI001190 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MUNSTER, VINCENT · 2014 to 2025
$3.4M
X-RAY CRYSTALLOGRAPHY OF HIV PROTEASEU01AI027220 · NIAID · ABBOTT LABORATORIES · PI ERICKSON, JOHN W · 1988 to 1992
–
Division of Intramural Research, National Institute of Allergy and Infectious Diseases HHSN 272201400006CMedical Research Council MR/P02551X/1U.S. Department of Homeland Security 2010-ST061-AG0001
6 · The paper itself

Abstract

Middle East respiratory syndrome-related coronavirus (MERS-CoV) is a persistent zoonotic pathogen with frequent spillover from dromedary camels to humans in the Arabian Peninsula, resulting in limited outbreaks of MERS with a high case-fatality rate. Full genome sequence data from camel-derived MERS-CoV variants show diverse lineages circulating in domestic camels with frequent recombination. More than 90% of the available full MERS-CoV genome sequences derived from camels are from just two countries, the Kingdom of Saudi Arabia (KSA) and United Arab Emirates (UAE). In this study, we employ a novel method to amplify and sequence the partial MERS-CoV genome with high sensitivity from nasal swabs of infected camels. We recovered more than 99% of the MERS-CoV genome from field-collected samples with greater than 500 TCID

Indexed as

Genetic VariationAnimalsCamelusCoronavirus InfectionsGenome, ViralJordanMiddle East Respiratory Syndrome CoronavirusPhylogenyRepublic of KoreaSaudi ArabiaUnited Arab EmiratesZoonosescoronavirusesMERS-CoVphylogenomicspopulation genomicsviral genomicszoonoses

Identifiers

PMID33807288
PMCPMC8067259
OpenAlexW3144380371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.