Evidence map›Paper›PMID 33807287›Full record

ArticleInternational journal of molecular sciences2021

Pharmacological Effects of Guava (

Hsiao-Chien Lin, Jin-Yuarn Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. The Anticancer Potential ofLife (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Active Ingredients fromCurrent issues in molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hsiao-Chien LinDepartment of Food Science and Biotechnology, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan.
Jin-Yuarn LinDepartment of Food Science and Biotechnology, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan.ORCID 0000-0002-9209-7959
National Chung Hsing University · TW

Funding

Ministry of Science and Technology, Taiwan NSC 102-2313-B-005-033-MY3 and MOST 107-2320-B-005-010-MY3
6 · The paper itself

Abstract

The inhibitory effects of purified fractions isolated from guava seed polysaccharides (GSPS) including guava seed polysaccharide fraction 1 (GSF1), GSF2, and GSF3 on prostate cancer cells remain unclear. To clarify the anti-prostate cancer potential, GSPS, GSF1, GSF2, and GSF3 were isolated using Sepharose 6B gel filtration chromatography to assay their inhibitory effects on prostate PC-3 cell growth with direct action or indirect immunotherapy using either splenocyte conditioned media (SCM) or macrophage conditioned media (MCM). Correlations between cytokine profiles in the conditioned media and pro-apoptotic gene expression levels in the corresponding treated PC-3 cells were analyzed. Results showed that GSPS, GSF1, GSF2, and GSF3, particularly GSF3, through either direct action or indirect treatments using SCM or MCM, significantly (

Indexed as

AnimalsApoptosisCell Line, TumorCell ProliferationCulture Media, ConditionedHumansImmunotherapyMaleMiceMice, Inbred BALB CPC-3 CellsPlant ExtractsPolysaccharidesProstateProstatic NeoplasmsPsidiumCulture Media, ConditionedPlant ExtractsPolysaccharidesFas geneGSF3guava seedpro-(Bax)/anti-apoptotic (Bcl-2) genesprostate cancerPsidium guajava L.

Identifiers

PMID33807287
PMCPMC8036945
OpenAlexW3145402500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.