Evidence map›Paper›PMID 33807284›Full record

Trial reportNutrients2021

Time-Restricted Eating for 12 Weeks Does Not Adversely Alter Bone Turnover in Overweight Adults.

Andrea J Lobene, Satchidananda Panda, Douglas G Mashek, Emily N C Manoogian, Kathleen M Hill Gallant, Lisa S Chow

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  14. Intermittent fasting and bone health: a bone of contention?The British journal of nutrition · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Andrea J LobeneDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Satchidananda PandaSalk Institute for Biological Studies, La Jolla, CA 92037, USA.
Douglas G MashekDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
Emily N C ManoogianSalk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0001-9718-9310
Kathleen M Hill GallantDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-1528-8161
Lisa S ChowDepartment of Medicine, Division of Diabetes, Endocrinology and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-6210-2307
University of Minnesota · USSalk Institute for Biological Studies · USPurdue University West Lafayette · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic SyndromeR01DK118278 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pam Rajendran Taub · 2018 to 2026
$5.3M
Prolonged Daily Fasting As a Viable Alternative to Caloric Restriction in At-Risk Obese HumansR01DK124484 · NIDDK · UNIVERSITY OF MINNESOTA · PI CHOW, LISA SENYE · 2020 to 2023
$2.7M
NRSA Training CoreTL1TR002531 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI FOTI, DANIEL JUSTIN, HURLEY, THOMAS D. · 2018 to 2022
$2.5M
Phosphorus Absorption and Balance in Normal Physiology and Chronic Kidney DiseaseK01DK102864 · NIDDK · UNIVERSITY OF MINNESOTA · PI GALLANT, KATHLEEN M HILL · 2015 to 2019
$692k
Healthy Foods, Healthy Lives Institute, University of Minnesota 17SFR-2YR50LCIndiana Clinical and Translational Sciences Institute UL1TR002529, TL1TR002531NCATS NIH HHS TL1 TR002531NCATS NIH HHS UL1 TR002494NCATS NIH HHS UL1TR002494NCATS NIH HHS UL1 TR002529NIDDK NIH HHS K01 DK102864NIDDK NIH HHS K01DK102864NIDDK NIH HHS R01DK118278NIDDK NIH HHS R01DK124484
6 · The paper itself

Abstract

Weight loss is a major focus of research and public health efforts. Time-restricted eating (TRE) is shown to be effective for weight loss, but the impact on bone is unclear. Short-term TRE studies show no effect on bone mineral density (BMD), but no study has measured bone turnover markers. This secondary analysis examined the effect of 12 weeks of TRE vs. unrestricted eating on bone turnover and BMD. Overweight and obese adults aged 18-65 y (

Indexed as

Feeding BehaviorAdultBiomarkersBone and BonesBone DensityFemaleHumansMaleMiddle AgedOverweightTime FactorsBiomarkersbone healthbone turnover markershumanstime-restricted eating

Identifiers

PMID33807284
PMCPMC8065778
OpenAlexW3140034407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.