Evidence map›Paper›PMID 33807211›Full record

ArticleInternational journal of environmental research and public health2021

Polybrominated Diphenyl Ether Serum Concentrations and Depressive Symptomatology in Pregnant African American Women.

Abby D Mutic, Dana Boyd Barr, Vicki S Hertzberg, Patricia A Brennan, Anne L Dunlop, Linda A McCauley

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Toxic Effects and Mechanisms of Polybrominated Diphenyl Ethers.International journal of molecular sciences · 2023
    Review
  10. Effects of UV radiation on natural and synthetic materials.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Abby D MuticNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0003-2374-622X
Dana Boyd BarrGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Vicki S HertzbergNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-8834-4363
Patricia A BrennanDepartment of Psychology, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0003-3742-2891
Anne L DunlopNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA.
Linda A McCauleyNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA.
Emory University · US

Funding

Microbiome, Environment, and Neurodevelopmental Delay (MEND)P50ES026071 · NIEHS · EMORY UNIVERSITY · PI RODRIGUEZ, DORIS JEAN · 2015 to 2018
$3.3M
Biobehavioral Determinants of the Microbiome and Preterm Birth in Black WomenR01NR014800 · NINR · EMORY UNIVERSITY · PI CORWIN, ELIZABETH JEANNE, DUNLOP, ANNE LANG · 2013 to 2017
$2.8M
EPA EPA83615301NIEHS NIH HHS P50ES026071NINR NIH HHS R01 NR014800
6 · The paper itself

Abstract

(1) Polybrominated diphenyl ethers (PBDEs) were widely produced in the United States until 2004 but remain highly persistent in the environment. The potential for PBDEs to disrupt normal neuroendocrine pathways resulting in depression and other neurological symptoms is largely understudied. This study examined whether PBDE exposure in pregnant women was associated with antenatal depressive symptomatology. (2) Data were collected from 193 African American pregnant women at 8-14 weeks gestation. Serum PBDEs and depressive symptoms were analyzed and a mixture effect was calculated. (3) Urban pregnant African American women in the Southeastern United States had a high risk of depression (27%) compared to the National average. Increased levels of PBDEs were found. BDE-47 and -99 exposures are significantly associated with depressive symptomatology in the pregnant cohort. The weighted body burden estimate of the PBDE mixture was associated with a higher risk of mild to moderate depression using an Edinburgh Depression Scale cutoff score of ≥10 (OR = 2.93; CI 1.18, 7.82). (4) Since antenatal depression may worsen in postpartum, reducing PBDE exposure may have significant clinical implications.

Indexed as

Halogenated Diphenyl EthersPregnant PeopleBlack or African AmericanBody BurdenFemaleHumansPregnancySoutheastern United StatesUnited StatesHalogenated Diphenyl Ethersantenatal depressionendocrine disrupting chemicalneuroendocrinepolybrominated diphenyl ether

Identifiers

PMID33807211
PMCPMC8037135
OpenAlexW3142978774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.