Evidence map›Paper›PMID 33807148›Full record

ArticleNutrients2021

Shikonin Derivatives from

Zeljko Todorovic, Jelena Milovanovic, Dragana Arsenijevic, Nenad Vukovic, Milena Vukic, Aleksandar Arsenijevic, Predrag Djurdjevic, Marija Milovanovic, Nebojsa Arsenijevic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Exploration of targeted anti-tumor therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zeljko TodorovicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Jelena MilovanovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Dragana ArsenijevicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-5357-2633
Nenad VukovicDepartment of Chemistry, Faculty of Science, University of Kragujevac, 34000 Kragujevac, Serbia.
Milena VukicDepartment of Chemistry, Faculty of Science, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-7222-7245
Aleksandar ArsenijevicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Predrag DjurdjevicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Marija MilovanovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Nebojsa ArsenijevicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
University of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antitumor effects of shikonins on chronic lymphocytic leukemia (CLL) and B-cell prolymphocytic leukemia (B-PLL) are mostly unexplored. The antitumor activity of shikonins, isolated from

Indexed as

AnimalsAntineoplastic Agents, PhytogenicApoptosisBoraginaceaeCell LineCell ProliferationCell SurvivalGene Expression Regulation, NeoplasticHumansInhibitory Concentration 50LeukemiaMaleMembrane ProteinsMiceMice, Inbred BALB CNaphthoquinonesAntineoplastic Agents, PhytogenicMembrane ProteinsNaphthoquinonesp112 protein, ratPhosphoproteinsshikoninSTAT3 protein, humanStat3 protein, mouseSTAT3 Transcription FactorBCL1isobutyrylshikoninJVM-13Onosma visianiiSTAT3α-methylbutyrylshikonin

Identifiers

PMID33807148
PMCPMC8065735
OpenAlexW3143381867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.