Evidence map›Paper›PMID 33807146›Full record

ReviewMicroorganisms2021

Antiviral Properties of Human Milk.

Sophie I S Wedekind, Natalie S Shenker

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Milk Antiviral Proteins and Derived Peptides against Zoonoses.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Antivirals and Vaccines.International journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Milk Fat Globules: 2024 Updates.Newborn (Clarksville, Md.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sophie I S WedekindDepartment of Surgery and Cancer, Imperial College London, London W12 0NN, UK.
Natalie S ShenkerDepartment of Surgery and Cancer, Imperial College London, London W12 0NN, UK.ORCID 0000-0002-8067-1079
Imperial College London · GBRothamsted Research · GB

Funding

Medical Research Council MR/S017437/1UK Research and Innovation p76489
6 · The paper itself

Abstract

Humans have always coexisted with viruses, with both positive and negative consequences. Evolutionary pressure on mammals has selected intrinsic properties of lactation and milk to support the relatively immunocompromised neonate from environmental pathogens, as well as support the normal development of diverse immune responses. Human milk supports both adaptive and innate immunity, with specific constituents that drive immune learning and maturation, and direct protection against microorganisms. Viruses constitute one of the most ancient pressures on human evolution, and yet there is a lack of awareness by both public and healthcare professionals of the complexity of human milk as an adaptive response beyond the production of maternal antibodies. This review identifies and describes the specific antiviral properties of human milk and describes how maternal support of infants through lactation is protective beyond antibodies.

Indexed as

global healthlactationtherapeuticsviruses

Identifiers

PMID33807146
PMCPMC8066736
OpenAlexW3148505188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.