Evidence map›Paper›PMID 33807096›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Ultrabright Green-Emitting Nanoemulsions Based on Natural Lipids-BODIPY Conjugates.

Xinyue Wang, Sophie Bou, Andrey S Klymchenko, Nicolas Anton, Mayeul Collot

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinyue WangFaculté de Pharmacie d'Illkirch, Université de Strasbourg, CNRS, CAMB UMR 7199, F-67000 Strasbourg, France.
Sophie BouFaculté de Pharmacie d'Illkirch, Université de Strasbourg, CNRS, LPB 7021, F-67000 Strasbourg, France.
Andrey S KlymchenkoFaculté de Pharmacie d'Illkirch, Université de Strasbourg, CNRS, LPB 7021, F-67000 Strasbourg, France.
Nicolas AntonFaculté de Pharmacie d'Illkirch, Université de Strasbourg, CNRS, CAMB UMR 7199, F-67000 Strasbourg, France.
Mayeul CollotFaculté de Pharmacie d'Illkirch, Université de Strasbourg, CNRS, LPB 7021, F-67000 Strasbourg, France.ORCID 0000-0002-8673-1730

Funding

China Scholarship Council ‭201706240033‬H2020 European Research Council 648528
6 · The paper itself

Abstract

Nanoemulsions (NEs) are water-dispersed oil droplets that constitute stealth biocompatible nanomaterials. NEs can reach an impressive degree of fluorescent brightness owing to their oily core that can encapsulate a large number of fluorophores on the condition the latter are sufficiently hydrophobic and oil-soluble. BODIPYs are among the brightest green emitting fluorophores and as neutral molecules possess high lipophilicity. Herein, we synthesized three different natural lipid-BODIPY conjugates by esterification of an acidic BODIPY by natural lipids, namely: α-tocopherol (vitamin E), cholesterol, and stearyl alcohol. The new BODIPY conjugates were characterized in solvents and oils before being encapsulated in NEs at various concentrations. The physical (size, stability over time, leakage) and photophysical properties (absorption and emission wavelength, brightness, photostability) are reported and showed that the nature of the lipid anchor and the nature of the oil used for emulsification greatly influence the properties of the bright NEs.

Indexed as

BODIPYbrightnessfluorescencefluorescence correlation spectroscopynanoemulsions

Identifiers

PMID33807096
PMCPMC8005018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.